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10 papers found.
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Repeat participation in annual cross-sectional surveys of drug users and its implications for analysis

ObjectiveWe sought to establish the extent of repeat participation in a large annual cross-sectional survey of people who inject drugs and assess its implications for analysis.ResultsWe used “porn star names” (the name of each participant’s first pet followed by the name of the first street in which they lived) to identify repeat participation in three Australian Illicit Drug...

Non-motor symptoms of Parkinson’s disease: the patient’s perspective

Kieran C. Breen 0 Gerda Drutyte 0 0 K. C. Breen (&) G. Drutyte Parkinson's UK, 215 Vauxhall Bridge Road, London SW1V 1EJ, UK Parkinson's disease (PD) can be manifested in many different ways

Proportional lumbar spine inter-vertebral motion patterns: a comparison of patients with chronic, non-specific low back pain and healthy controls

3LT, UK 1 F. E. Mellor P. Thompson School of Health and Social Care, Bournemouth University , Bournemouth BH1 3LT, UK 2 F. E. Mellor A. C. Breen (&) Institute for Musculoskeletal Research and Clinical

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific roles of most endogenous siRNAs are unclear. The helicase gene eri-6/7 was identified in the nematode Caenorhabditis elegans by the...

A genomics approach to understanding the role of auxin in apple (Malus x domestica) fruit size control

Payne 0 Toby John Ling John James Ross Ian Charles Hallett Kularajathevan Gunaseelan GA Dayatilake Robert Diak Ken C Breen D Stuart Tustin Evelyne Costes David Chagn Robert James Schaffer 0 Karine Myriam

Autoinsertion of soluble oligomers of Alzheimer's Aβ(1–42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface

Background Soluble Alzheimer's Aβ oligomers autoinsert into neuronal cell membranes, contributing to the pathology of Alzheimer's Disease (AD), and elevated serum cholesterol is a risk factor for AD, but the reason is unknown. We investigated potential connections between these two observations at the membrane level by testing the hypothesis that Aβ(1–42) relocates membrane...

Associations of Non-Hodgkin Lymphoma (NHL) Risk With Autoimmune Conditions According to Putative NHL Loci

University, Detroit, Michigan (Richard Severson); Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, California (Elizabeth C. Breen); Department of

Birth Order and Risk of Non-Hodgkin Lymphoma—True Association or Bias?

There is inconsistent evidence that increasing birth order may be associated with risk of non-Hodgkin lymphoma (NHL). The authors examined the association between birth order and related variables and NHL risk in a pooled analysis (1983–2005) of 13,535 cases and 16,427 controls from 18 case-control studies within the International Lymphoma Epidemiology Consortium (InterLymph...

Tissue-specific regulation of sialyltransferase activities in the rat by corticosteroids in vivo

In this study we have examined the effects of corticosteroids on both the total sialyltransferase (sialyl-T) activity and on two individual isozymes in neural, hepatic, and renal tissues using an in vivo model system. Rats were adrenalectomised to deplete their endogenous stores of steroid hormones, and some subsequently received steroid replacement with dexamethasone or...