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Real-world effectiveness of peginterferon α-2b plus ribavirin in a Canadian cohort of treatment-naïve chronic hepatitis C patients with genotypes 2 or 3: results of the PoWer and RediPEN studies

The purpose of this investigation was to assess the real-life effectiveness of pegylated interferon (peg-IFN) α-2b with ribavirin (RBV) in a cohort of treatment-naïve patients with chronic genotypes 2 (G2) or 3 (G3) hepatitis C virus (HCV) infection. A post-hoc pooled analysis of two Canadian multicenter, observational studies, RediPEN and PoWer, was carried out. A total of 1242...

Ion Channel Expression in the Developing Enteric Nervous System

The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemistry. Many ion channels, including chloride, calcium, potassium and sodium channels were already expressed by ENCCs at E11.5. There...

Galaxy assembly bias on the red sequence

M. C. Cooper et al. 0 Department of Physics and Astronomy, University of Pittsburgh , 401-C Allen Hall, 3941 O'Hara Street, Pittsburgh, PA 15260, USA 1 Max-Planck-Institut fur Astronomie , Konigstuhl

Claudin 1 expression in basal-like breast cancer is related to patient age

Background Defects in tight junctions, gate-keepers of the integrity of the epidermal barrier function, are known to contribute to cancer development. As such, enhancing our understanding of how the expression of proteins involved in these junctions is regulated in cancer, remains a priority. Although the expression of one of these proteins, claudin 1, is down regulated in most...

Erratum to: Impact of nutrition on muscle mass, strength, and performance in older adults

, Belgium 2 J.-P. Bonjour 3 N. Yoshimura Department of Joint Disease Research, 22nd Century Medical and Research Center, The University of Tokyo , Tokyo , Japan 4 C. Cooper NIHR Musculoskeletal Biomedical ... Research Unit, Institute of Musculoskeletal Sciences, University of Oxford , Oxford , UK 5 C. Cooper MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital , Southampton

The DEEP2 Galaxy Redshift Survey: environments of post-starburst galaxies at z∼ 0.1 and ∼0.8

Post-starburst (also known as K+A) galaxies exhibit spectroscopic signatures indicating that their star formation was recently quenched; they are candidates for galaxies in transition from a star-forming phase to a passively evolving phase. We have spectroscopically identified large samples of post-starburst galaxies both in the Sloan Digital Sky Survey (SDSS) at z∼ 0.1 and in...

On the evolution of the velocity–mass–size relations of disc-dominated galaxies over the past 10 billion years

We study the evolution of the scaling relations between the maximum circular velocity, stellar mass and optical half-light radius of star-forming disc-dominated galaxies in the context of Λ cold dark matter-based galaxy formation models. Using data from the literature combined with new data from the Deep Extragalactic Evolutionary Probe 2 (DEEP2) and All-wavelength Extended Groth...

Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Department of Medicine, Hospital del Mar-IMIM-Autonomous, University of Barcelona , Barcelona, Spain 8 C. Cooper Institute of Musculoskeletal Sciences, University of Oxford , Oxford, UK 9 C. Cooper MRC

Absence of evidence is not evidence of absence: the colour–density relation at fixed stellar mass persists to z∼ 1*

M. C. Cooper et al. E-mail: 0 0 Some of the data presented herein were obtained at the W. M. Keck Ob- servatory, which is operated as a scientific partnership among the California Institute of

The DEEP2 Galaxy Redshift Survey: the role of galaxy environment in the cosmic star formation history

Using galaxy samples drawn from the Sloan Digital Sky Survey and the DEEP2 Galaxy Redshift Survey, we study the relationship between star formation and environment at z∼ 0.1 and 1. We estimate the total star formation rate (SFR) and specific star formation rate (sSFR) for each galaxy according to the measured [O ii]λ 3727 Å nebular line luminosity, corrected using empirical...

The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design

8 P. Delmas Department of Rheumatology , Hpital Edouard Herriot, 5 Place d'Arsonval, Lyon, France 69437 9 C. Cooper Institute of Musculoskeletal Sciences, University of Oxford , Oxford, UK 10 J ... . Pfeilschifter Alfried Krupp Krankenhaus, Department of Internal Medicine III , Essen, Germany 11 C. Cooper MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital , Southampton

A deep Chandra survey of the Groth Strip – II. Optical identification of the X-ray sources

In this paper, we discuss the optical and X-ray spectral properties of the sources detected in a single 200-ks Chandra pointing in the Groth-Westphal Strip region. A wealth of optical photometric and spectroscopic data are available in this field providing optical identifications and redshift determinations for the X-ray population. The optical photometry and spectroscopy used...