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Muscle Mass, Muscle Morphology and Bone Health Among Community-Dwelling Older Men: Findings from the Hertfordshire Sarcopenia Study (HSS)

Sarcopenia and osteoporosis are associated with poor health outcomes in older people. Relationships between muscle and bone have typically been reported at a functional or macroscopic level. The aims of this study were to describe the relationships between muscle morphology and bone health among participants of the Hertfordshire Sarcopenia Study (HSS). 105 older men, mean age 72...

Correlates of Level and Loss of Grip Strength in Later Life: Findings from the English Longitudinal Study of Ageing and the Hertfordshire Cohort Study

contributed equally to the manuscript. C. Cooper and C. R. Gale are senior authors and contributed equally to the manuscript characterised using mixed-effects models in ELSA and a residual change approach in ... accountable for the work. Compliance with Ethical Standards Conflict of interest H. E. Syddall, L. D. Westbury, S. C. Shaw, E. M. Dennison, C. Cooper, and C. R. Gale declare that they have no conflict of

Epidemiology of Sarcopenia: Determinants Throughout the Lifecourse

Sarcopenia is an age-related syndrome characterised by progressive and generalised loss of skeletal muscle mass and strength; it is a major contributor to the risk of physical frailty, functional impairment in older people, poor health-related quality of life and premature death. Many different definitions have been used to describe sarcopenia and have resulted in varying...

Bone Phenotype Assessed by HRpQCT and Associations with Fracture Risk in the GLOW Study

they have no conflict of interest. C Cooper reports personal fees from Alliance for Better Bone Health, Amgen, Eli Lilly, GSK, Medtronic, Merck, Novartis, Pfizer, Roche, Servier, Takeda and UCB

Relationships Between Markers of Inflammation and Muscle Mass, Strength and Function: Findings from the Hertfordshire Cohort Study

and C. Cooper declare that they have no conflict of interest. Ethical Approval The baseline Hertfordshire Cohort Study had ethical approval from the Hertfordshire and Bedfordshire Local Research Ethics

Non-invasive Assessment of Lower Limb Geometry and Strength Using Hip Structural Analysis and Peripheral Quantitative Computed Tomography: A Population-Based Comparison

. J. Denison, K. A. Jameson, M. H. Edwards, A. A. Sayer, P. Taylor, C. Cooper, E. M. Dennison) declare no conflict of interest Human and Animal Rights and Informed Consent Ethical permission for the

Use of β-Blockers and the Risk of Hip/Femur Fracture in the United Kingdom and The Netherlands

Data from in vivo studies have indicated a role for β-blockers in the prevention of bone loss. Some epidemiological studies have found protective effects of β-blockers on fracture risk. However, there is limited information on the association with cumulative dose and type of β-blockers used. We conducted two case-control studies using data from the UK General Practice Research...

Sex Hormones and Osteoporosis in Men

) Effect of testosterone and estradiol in a man with aromatase deficiency . N Engl J Med 337 : 91 - 95 30. Anderson FH , Francis RM , Hindmarsh P , Fall C , Cooper C ( 1996 ) Serum oestradiol in osteoporotic