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Search: authors:"Carel G. M. Meskers"

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Lack of knowledge and availability of diagnostic equipment could hinder the diagnosis of sarcopenia and its management

attendance, total and stratified by group of health Conceptualization: Esmee M. Reijnierse, Marian A. E. de van der Schueren, Marijke C. Trappenburg, Marjan Doves, Carel G. M. Meskers, Andrea B. Maier. Data ... curation: Esmee M. Reijnierse. Formal analysis: Esmee M. Reijnierse. Methodology: Esmee M. Reijnierse, Marian A. E. de van der Schueren, Marijke C. Trappenburg, Marjan Doves, Carel G. M. Meskers, Andrea B

Reliability of System Identification Techniques to Assess Standing Balance in Healthy Elderly

Objectives System identification techniques have the potential to assess the contribution of the underlying systems involved in standing balance by applying well-known disturbances. We investigated the reliability of standing balance parameters obtained with multivariate closed loop system identification techniques. Methods In twelve healthy elderly balance tests were performed ...

The Association between Parameters of Malnutrition and Diagnostic Measures of Sarcopenia in Geriatric Outpatients

Objectives Diagnostic criteria for sarcopenia include measures of muscle mass, muscle strength and physical performance. Consensus on the definition of sarcopenia has not been reached yet. To improve insight into the most clinically valid definition of sarcopenia, this study aimed to compare the association between parameters of malnutrition, as a risk factor in sarcopenia, and ...

Poor motor function is associated with reduced sensory processing after stroke

The possibility to regain motor function after stroke depends on the intactness of motor and sensory pathways. In this study, we evaluated afferent sensory pathway information transfer and processing after stroke with the coherence between cortical activity and a position perturbation (position-cortical coherence, PCC). Eleven subacute stroke survivors participated in this study. ...

Blood Pressure Associates with Standing Balance in Elderly Outpatients

Objectives Assessment of the association of blood pressure measurements in supine and standing position after a postural change, as a proxy for blood pressure regulation, with standing balance in a clinically relevant cohort of elderly, is of special interest as blood pressure may be important to identify patients at risk of having impaired standing balance in routine geriatric ...

Familial Longevity Is Marked by Better Cognitive Performance at Middle Age: The Leiden Longevity Study

Background Decline in cognitive performance is a highly prevalent health condition in elderly. We studied whether offspring of nonagenarian siblings with a familial history of longevity, perform better on cognitive tests compared to their partners as controls. This is relevant since it could provide insights into determinants underlying decline in cognitive performance. Methods ...

Tizanidine does not affect the linear relation of stretch duration to the long latency M2 response of m. flexor carpi radialis

The long latency M2 electromyographic response of a suddenly stretched active muscle is stretch duration dependent of which the nature is unclear. We investigated the influence of the group II afferent blocker tizanidine on M2 response characteristics of the m. flexor carpi radialis (FCR). M2 response magnitude and eliciting probability in a group of subjects receiving 4 mg of ...

Arm load magnitude affects selective shoulder muscle activation

For isometric tasks, shoulder muscle forces are assumed to scale linearly with the external arm load magnitude, i.e., muscle force ratios are constant. Inverse dynamic modeling generally predicts such linear scaling behavior, with a critical role for the arbitrary load sharing criteria, i.e., the “cost function”. We tested the linearity of the relation between external load ...

The monosynaptic Ia afferent pathway can largely explain the stretch duration effect of the long latency M2 response

Sudden stretch of active muscle typically results in two characteristic electromyographic responses: the short latency M1 and the long latency M2. The M1 response originates from the monosynaptic Ia afferent reflex pathway. The M2 response is less well understood and is likely a compound response to different afferent inputs mediated by spinal and transcortical pathways. In this ...