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New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation

, Valencia, SpainMari Carmen González-Calixto & José Manuel García-VerdugoVall d’Hebrón Institut de Recerca (VHIR), Barcelona, SpainEduardo Soriano AuthorsSearch for Agata Mata in:Nature Research journals ... Miguel Dasilva in:Nature Research journals • PubMed • Google Scholar Search for Mari Carmen González-Calixto in:Nature Research journals • PubMed • Google Scholar Search for Eduardo Soriano in:Nature

Carotid ultrasound is useful for the cardiovascular risk stratification in patients with hidradenitis suppurativa

Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease which has been associated with an increased risk of adverse cardiovascular (CV) outcomes. Adequate stratification of the CV risk is an issue of major importance in patients with HS. To analyze the usefulness of carotid ultrasound (US) assessment for the CV disease risk stratification compared...

Secondary Mosques in Madinat Qurtuba: Islamization and Suburban Development through Minor Religious Spaces

Mosques are the most obvious materialization of Islam. They are a clear sign of its presence in a particular territory, the building where the history and influence of Islamic governments is reflected through their artistic elements and architectural variants. However, they are also essential for the everyday life of the neighborhoods they belong to, because their inhabitants...

Análisis de oportunidades y transferencia de información en la implantación de la trazabilidad de productos pesqueros. Una aplicación empírica para el sector congelador y conservero gallego

Los objetivos de este trabajo han sido dos. Por un lado, investigar las principales oportunidades que se presentan en el sector pesquero a la hora de implantar la trazabilidad y, por otro lado, analizar la gestión documental que realizan las empresas del sector congelador y conservero gallego e identificar los principales retos. Se han encuestado a técnicos del sector congelador...

Quantitative proteomics reveals the importance of nitrogen source to control glucosinolate metabolism in Arabidopsis thaliana and Brassica oleracea

Accessing different nitrogen (N) sources involves a profound adaptation of plant metabolism. In this study, a quantitative proteomic approach was used to further understand how the model plant Arabidopsis thaliana adjusts to different N sources when grown exclusively under nitrate or ammonium nutrition. Proteome data evidenced that glucosinolate metabolism was differentially...

Long term effects of fetal undernutrition on rat heart. Role of hypertension and oxidative stress

Background and aims Fetal undernutrition is a risk factor for heart disease in both genders, despite the protection of women against hypertension development. Using a rat model of maternal undernutrition (MUN) we aimed to assess possible sex differences in the development of cardiac alterations and the implication of hypertension and cardiac oxidative stress. Methods Male and...

Insulin Resistance in Adipose Tissue but Not in Liver Is Associated with Aortic Valve Calcification

 Marco A. Rodas-Díaz,2 Rosalinda Posadas-Sánchez,1 Gilberto Vargas-Alarcón,3 María del Carmen González-Salazar,1 Guillermo C. Cardoso-Saldaña,1 and Juan G. Juárez-Rojas1 1Endocrinology Department ... data, and final approval of the manuscript submitted. Margarita Torres-Tamayo, Aida X. Medina-Urrutia, Marco A. Rodas-Díaz, Rosalinda Posadas-Sánchez, Gilberto Vargas-Alarcón, María del Carmen González

Adipose tissue dysfunction increases fatty liver association with pre diabetes and newly diagnosed type 2 diabetes mellitus

Background To evaluate the role of adipose tissue function on the association of fatty liver (FL) with impaired fasting glucose (IFG) or newly diagnosed type 2 diabetes mellitus (nT2D). Methods In 1264 subjects, computed tomography was used to evaluate FL and elevated visceral adipose tissue (VAT). Fasting plasma glucose, <5.6, 5.6–6.9 and ≥7 mmol/l, were used to defined...

Looking for adaptive footprints in the HSP90AA1 ovine gene

Background Climatic factors play an important role in determining species distributions and phenotypic variation of populations over geographic space. Since domestic sheep is managed under low intensive systems animals could have retained some genome adaptive footprints. The gene encoding the Hsp90α has been extensively studied in sheep and some polymorphisms located at its...

Endothelial and Neuronal Nitric Oxide Activate Distinct Pathways on Sympathetic Neurotransmission in Rat Tail and Mesenteric Arteries

Nitric oxide (NO) seems to contribute to vascular homeostasis regulating neurotransmission. This work aimed at assessing the influence of NO from different sources and respective intracellular pathways on sympathetic neurotransmission, in two vascular beds. Electrically-evoked [3H]-noradrenaline release was assessed in rat mesenteric and tail arteries in the presence of NO donors...

Exploring ammonium tolerance in a large panel of Arabidopsis thaliana natural accessions

Plants are dependent on exogenous nitrogen (N) supply. Ammonium (NH4 +), together with nitrate (NO3 –), is one of the main nitrogenous compounds available in the soil. Paradoxically, although NH4 + assimilation requires less energy than that of NO3 –, many plants display toxicity symptoms when grown with NH4 + as the sole N source. However, in addition to species-specific...

Association of Trabecular Bone Score with Inflammation and Adiposity in Patients with Psoriasis: Effect of Adalimumab Therapy

Pina,2 Sheila Ruiz,1 Isabel Sierra,1 Begoña Ubilla,2 Verónica Mijares,2 Marcos A. González-López,3 Susana Armesto,3 Alfonso Corrales,2 Enar Pons,2 Patricia Fuentevilla,2 Carmen González-Vela,4 and Miguel

Identification and quantification of two species of oyster larvae using real-time PCR

A real-time polymerase chain reaction (PCR) assay was developed for the identification and quantification of two oyster species: Ostrea edulis and Crassostrea gigas. Two sets of primers and TaqMan-MGB probes were designed, based on partial sequences of the 16S rRNA gene. An amplification positive control system was also located in the 18S rRNA gene sequences. Closely related...

EGFR testing and clinical management of advanced NSCLC: a Galician Lung Cancer Group study (GGCP 048-10)

Santomé,5 Francisco Barón,6 Martín Lázaro,7 Carolina Pena,7 Margarita Amenedo,8 Ihab Abdulkader,9 Carmen González-Arenas,10 Laura Fachal,11 Ana Vega11 On behalf of the Galician Lung Cancer Group (GGCP ... Francisco Javier afonso afonso 3 Margarita amenedo 8 ihab abdulkader 9 Carmen gonzález-arenas 10 laura Fachal 11 ana Vega 11 On behalf of the g alician l ung Cancer group (ggCP) augusti University

Differences in the Ovine HSP90AA1 Gene Expression Rates Caused by Two Linked Polymorphisms at Its Promoter Affect Rams Sperm DNA Fragmentation under Environmental Heat Stress Conditions

Heat shock (HS) is one of the best-studied exogenous cellular stresses. Almost all tissues, cell types, metabolic pathways and biochemical reactions are affected in greater or lesser extent by HS. However, there are some especially thermo sensible cellular types such as the mammalian male germ cells. The present study examined the role of three INDELs in conjunction with the...

The effects of differential outcomes and different types of consequential stimuli on 7-year-old children’s discriminative learning and memory

Researchers have demonstrated that discriminative learning is facilitated when a particular outcome is associated with each relation to be learned. Our primary purpose in the two experiments reported here was to assess whether the differential outcomes procedure (DOP) would enhance 7-year-old children’s learning of symbolic discriminations using three different forms of...

Interpreting finite element results for brittle materials in endodontic restorations

Background Finite element simulation has been used in last years for analysing the biomechanical performance of post-core restorations in endodontics, but results of these simulations have been interpreted in most of the works using von Mises stress criterion. However, the validity of this failure criterion for brittle materials, which are present in these restorations, is...

Orthokeratinized Odontogenic Cyst: A Report of Three Clinical Cases

. Epivatianos, A. Markopoulos, and G. Sammartino Copyright © 2013 María del Carmen González Galván et al. This is an open access article distributed under the Creative Commons Attribution License, which permits ... . Acknowledgment This work was supported by grants from the Department of Education, Universities and Research, Government of the Basque Country (IT-192-07). María del Carmen González Galván is supported by a