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19 papers found.
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Prediction of absolute risk of acute graft-versus-host disease following hematopoietic cell transplantation

Wang. Formal analysis: Catherine Lee, Sebastien Haneuse. Investigation: Michael Verneris, Katharine C. Hsu, Stephanie J. Lee, Reza Abdi. 13 / 16 Methodology: Sebastien Haneuse, Sherri Rose, Stephen R ... . Spellman, Katharina Fleischhauer, Stephanie J. Lee. Writing ± original draft: Sebastien Haneuse. Writing ± review & editing: Catherine Lee, Hai-Lin Wang, Sherri Rose, Stephen R. Spellman, Michael

How the Foreign Corrupt Practices Act Can Help Referee FIFA

Practices Act Can Help Referee FIFA CATHERINE LEE† INTRODUCTION The Fédération Internationale de Football Association, known as FIFA, states that it “has a zero-tolerance policy towards wrongdoing of any ... -century, international efforts have focused on increasing accountability of international organizations and businesses to reduce corruption,4 yet many countries’ laws do not regulate the © 2016 Catherine

A fixed point theorem for smooth extension maps

Let X be a compact smooth n-manifold, with or without boundary, and let A be an -dimensional smooth submanifold of the interior of X. Let be a smooth map and be a smooth map whose restriction to A is ϕ. If is an isolated fixed point of f that is a transversal fixed point of ϕ, that is, the linear transformation is nonsingular, then the fixed point index of f at p satisfies the ...

Arx Polyalanine Expansion in Mice Leads to Reduced Pancreatic α-Cell Specification and Increased α-Cell Death

Expansion in Mice Leads to Reduced Pancreatic a-Cell Specification and Increased a-Cell Death Crystal L. Wilcox 0 Natalie A. Terry 0 Catherine Lee May 0 Henrik Einwaechter, Klinikum rechts der Isar der TU Mu

Factors associated with grade 1 hypertension: implications for hypertension care based on the Dietary Approaches to Stop Hypertension (DASH) in primary care settings

Background A Reference Framework for Hypertension Care was recently developed by Hong Kong government to emphasise the importance of primary care for subjects with high blood pressure (BP). The Dietary Approaches to Stop Hypertension (DASH) interventional regime was recommended for patients aged 40–70 years with grade 1 hypertension (having systolic BP of 140-159 mmHg and/or ...

A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders: Development and Outcomes of a Randomized Controlled Trial among Burmese Refugees in Thailand

In a randomized controlled trial, Paul Bolton and colleagues investigate whether a transdiagnostic community-based intervention is effective for improving mental health symptoms among Burmese refugees in Thailand. Please see later in the article for the Editors' Summary

Interior fixed points of unit-sphere-preserving Euclidean maps

Schirmer proved that there is a class of smooth self-maps of the unit sphere in Euclidean n-space with the property that any smooth self-map of the unit ball that extends a map of that class must have at least one fixed point in the interior of the ball. We generalize Schirmer’s result by proving that a smooth self-map of Euclidean n-space that extends a self-map of the unit sphere ...

Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

A. Lee 0 Catherine Lee May 0 Kathrin Maedler, University of Bremen, Germany 0 1 Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United

Recognizing thyrotoxicosis in a patient with bipolar mania: a case report

Background A thyroid stimulating hormone level is commonly measured in patients presenting with symptoms of mania in order to rule out an underlying general medical condition such as hyperthyroidism or thyrotoxicosis. Indeed, many cases have been reported in which a patient is initially treated for bipolar mania, but is later found to have a thyroid condition. Several case reports ...

Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

Chad S. Hunter Shilpy Dixit Tsadok Cohen Benjamin Ediger Crystal Wilcox Mark Ferreira Heiner Westphal Roland Stein Catherine Lee May Ldb1 and Ldb2 are coregulators that mediate Lin11-Isl1-Mec3 (LIM

Timing of Axillary Staging

. Catherine Lee, MD Optimal timing of axillary staging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy remains a contentious issue among surgical oncologists. Our group at

Serum S100B: A Potential Biomarker for Suicidality in Adolescents?

Background Studies have shown that patients suffering from depression or schizophrenia often have immunological alterations that can be detected in the blood. Others reported a possible link between inflammation, a microgliosis and the blood-brain barrier (BBB) in suicidal patients. Serum S100B is a marker of BBB function commonly used to study cerebrovascular wall function. ...

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Such knowledge would improve our ability to correctly program or reprogram cells to adopt specific endocrine fates. Here, we show that ...

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

Aiping Du Chad S. Hunter Johanna Murray Daniel Noble Chen-Leng Cai Sylvia M. Evans Roland Stein Catherine Lee May OBJECTIVE-The generation of mature cell types during pancreatic development depends

Defining Pancreatic Endocrine Precursors and Their Descendants

Peter White Catherine Lee May Rodrigo N. Lamounier John E. Brestelli Klaus H. Kaestner OBJECTIVE-The global incidence of diabetes continues to increase. Cell replacement therapy and islet


BACKGROUND: LMD in children with recurrent medulloblastoma and other PNETs carries a poor prognosis and novel therapies are urgently needed to improve disease control. Somatostatin receptor-2 (SSR-2)is overexpressed in medulloblastoma and other central PNETs and can serve as a target for radionuclide tagged somatostatin analogues like 177Lu-DOTA-TATE that has shown considerable ...