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Search: authors:"Chandrasai Potla Durthi"

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Molecular dynamic simulations of Escherichia coli l-asparaginase to illuminate its role in deamination of asparagine and glutamine residues

Acute lymphocytic leukemia (ALL) is an outrageous disease worldwide. l-Asparagine (l-Asn) and l-Glutamine (l-Gln) deamination play a crucial role in ALL treatment. Role of ElsparĀ® (l-asparaginase from Escherichia coli) in regulation of l-Asn and l-Gln has been confirmed by the other researchers through experimental studies. Therapeutic research against ALL remained elusive with...

Studies on removal of arsenic using cellulose acetateā€“zinc oxide nanoparticle mixed matrix membrane

Mixed matrix membranes prepared by varying compositions of Cellulose acetate, acetone and formamide for the synthesis of ultrafiltration/nanofiltration membranes with and without nanoparticles for the removal of arsenic from synthetic solution. Zinc oxide nanoparticles were synthesized by an in situ ultrasonic technique and characterization done using XRD and SEM. In the current...