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Short-term Effect of Ambient Ozone on Daily Emergency Room Visits in Beijing, China

Little is known about the acute effects of ozone on morbidity risk in China. We conducted a time-series study to examine the association between ozone and daily emergency room visits (ERVs) in Beijing, China. We identified 7,088,309 ERVs between January 1, 2014 and December 31, 2015. A generalized additive model with Poisson regression incorporating penalized spline functions was...

The effects of dipeptidyl peptidase-4 inhibitors on bone fracture among patients with type 2 diabetes mellitus: A network meta-analysis of randomized controlled trials

Wu. Data curation: Jun Yang, Chao Huang, Yang Xu, Ting Cai, Sanbao Chai. Formal analysis: Jun Yang, Chao Huang, Zhirong Yang. Funding acquisition: Siyan Zhan. Methodology: Jun Yang, Shanshan Wu ... . Supervision: Feng Sun, Siyan Zhan. Validation: Yang Xu. Writing ± original draft: Chao Huang. Writing ± review & editing: Feng Sun. 17 / 20 18 / 20 19 / 20 1. Fadini GP , Bonora BM , Cappellari R , Menegazzo

Evaluation of 99mTc-3PRGD2 integrin receptor imaging in hepatocellular carcinoma tumour-bearing mice: comparison with 18F-FDG metabolic imaging

Objective Our study was designed to explore the utility of 99mTc-HYNIC-PEG4-E[PEG4-c(RGDfK)]2 (99mTc-3PRGD2) for the detection of hepatocellular carcinoma (HCC) and specifically to compare the diagnostic performance of 99mTc-3PRGD2 integrin receptor imaging and 2-18-fluoro-2-deoxy-d-glucose (18F-FDG) metabolic imaging in a nude mouse model. Methods 99mTc-3PRGD2 was synthesized...

Large-scale cross-species chemogenomic platform proposes a new drug discovery strategy of veterinary drug from herbal medicines

Huang. 17 / 20 Data curation: Chao Huang, Yang Yang, Xuetong Chen, Chao Wang, Chunli Zheng. Formal analysis: Chao Huang. Funding acquisition: Yonghua Wang. Methodology: Chao Huang, Yang Yang, Chao Wang ... , Yan Li, Chunli Zheng, Yonghua Wang. Software: Chao Wang, Yan Li, Yonghua Wang. Validation: Yang Yang, Xuetong Chen, Chunli Zheng. Visualization: Chao Huang, Xuetong Chen, Yan Li, Chunli Zheng. Writing

Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer

Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer Hong Liu, Chao Huang, Liyun Wu, Bin Wen Institute of Spleen and Stomach, Guangzhou University of Chinese ... OncoTargets and Therapy effect of evodiamine and berberine on mir-429 as an oncogene in human colorectal cancer hong liu chao huang liyun Wu Bin Wen Loss of epithelial organization and deregulated

Mechanistic insights into the effect of imidazolium ionic liquid on lipid production by Geotrichum fermentans

Lou 0 Ning Li 0 Chao Huang Hong Wu 0 0 School of Food Science and Engineering, South China University of Technology , Room 409, Building 13, 381 Wushan Rd., Tianhe District, Guangzhou 510640 , China

Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway

Ren and Chao Huang contributed equally to this paper. Acknowledgments The authors would like to express their great gratitude to the editor and all three anonymous reviewers who provided them with

XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell

Background The X-linked inhibitor of apoptosis protein (XIAP) is a well-known potent apoptosis suppressor and also participates in cancer cell biological behaviors, therefore attracting great attentions as a potential antineoplastic therapeutic target for past years. Anti-IAP therapy is reported to be closely related to epidermal growth factor receptor (EGFR) expression level...

Combination of Biorthogonal Wavelet Hybrid Kernel OCSVM with Feature Weighted Approach Based on EVA and GRA in Financial Distress Prediction

Academic Editor: Wei-Chiang Hong Copyright © 2014 Chao Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution

Retinal vein occlusion in retinal racemose hemangioma: a case report and literature review of ocular complications in this rare retinal vascular disorder

Backgroud Retinal racemose hemangioma (RRH) is a rare congenital disorder that often co-occurs with other ocular complications. In this study, we present a case of RRH complicated with retinal vein obstruction in three branches and provide a review of ocular complications and associations with RRH. Case presentation One case of RRH is presented. Fundus examination, fluorescein...

Sensitivity and Specificity of Cardiac Tissue Discrimination Using Fiber-Optics Confocal Microscopy

Disturbances of the cardiac conduction system constitute a major risk after surgical repair of complex cases of congenital heart disease. Intraoperative identification of the conduction system may reduce the incidence of these disturbances. We previously developed an approach to identify cardiac tissue types using fiber-optics confocal microscopy and extracellular fluorophores...

Design, synthesis and biological evaluation of hybrids of β-carboline and salicylic acid as potential anticancer and apoptosis inducing agents

Drug Target, Nantong University, Nantong 226001, ChinaQi-Bing Xu, Xiang-Fan Chen, Jiao Feng, Ji Liu, Feng-Tao Liu, Bi-Xi Niu, Jin-Yang Cai, Chao Huang, Yanan Zhang & Yong LingState Key Laboratory of ... Chao Huang in:Nature Research journals • PubMed • Google ScholarSearch for Yanan Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Yong Ling in:Nature Research journals • PubMed

Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microglia

authors read and approved the final manuscript. Acknowledgements This work was supported by the Natural Science Foundation of Jiangsu Province to Dr Chao Huang (No. BK20141240), the National Natural ... Science Foundation of China Dr Chao Huang (No. 81102428), and the Priority Academic Program Development of Jiangsu Higher Education Institutions. 1. O'Connor DM , O'Brien T. Nitric oxide synthase gene

Systems-Pharmacology Dissection of Traditional Chinese Medicine Compound Saffron Formula Reveals Multi-scale Treatment Strategy for Cardiovascular Diseases

 & Jiexin MuCollege of Life Science, Northwest A & F University, Yangling, Shaanxi 712100, ChinaJianling Liu, Jiexin Mu, Chunli Zheng, Xuetong Chen, Zihu Guo, Chao Huang, Yingxue Fu & Yonghua WangCenter of ... Bioinformatics, Northwest A & F University, Yangling, Shaanxi 712100, ChinaJianling Liu, Jiexin Mu, Chunli Zheng, Xuetong Chen, Zihu Guo, Chao Huang, Yingxue Fu & Yonghua WangKey laboratory of Chinese internal

Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy

Diabetic retinopathy is a sight-threatening complication of diabetes, affecting 65% of patients after 10 years of the disease. Diabetic metabolic insult leads to chronic low-grade inflammation, retinal endothelial cell loss and inadequate vascular repair. This is partly due to bone marrow (BM) pathology leading to increased activity of BM-derived pro-inflammatory monocytes and...

Levee failure mechanisms during the extreme rainfall event: a case study in Southern Taiwan

Extreme weather has recently caused many disasters worldwide. In August 8, 2009, Southern Taiwan suffered from serious floods during Typhoon Morakot. In this extreme rainfall event, the Chiuliao first levee in the Laonong River basin experienced catastrophic failure. Therefore, this study focuses on the levee failure mechanisms based on variations in levee water levels...

Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM

Holistic medicine is an interdisciplinary field of study that integrates all types of biological information (protein, small molecules, tissues, organs, external environmental signals, etc.) to lead to predictive and actionable models for health care and disease treatment. Despite the global and integrative character of this discipline, a comprehensive picture of holistic...

Association of polymorphisms in AGTR1 and AGTR2 genes with primary aldosteronism in the Chinese Han population

Hypothesis: Polymorphisms in angiotensin II type-1/2 receptor genes (AGTR1/AGTR2) may be involved in the pathogenesis of primary aldosteronism. The present study aims to reveal some loci susceptible to the disease on the genes in a group of Chinese Han nationality.