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Search: authors:"Chao Niu"

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Effect of all-trans retinoic acid on the proliferation and differentiation of brain tumor stem cells

Objective To investigate the effect of all-trans retinoic acid(ATRA) on the proliferation and differentiation of brain tumor stem cells(BTSCs) in vitro. Methods Limiting dilution and clonogenic assay were used to isolate and screen BTSCs from the fresh specimen of human brain glioblastoma. The obtained BTSCs, which were cultured in serum-free medium, were classified into four ...