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6 papers found.
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Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa

: Constantin T. Yiannoutsos, Beverly S. Musick, Carolyn Williams, Kara K. Wools-Kaloustian. Funding acquisition: Craig Cohen. Investigation: Charles B. Holmes, Constantin T. Yiannoutsos, Batya Elul, Elizabeth ... . Musick, Carolyn Williams, Nancy Padian, Kara K. Wools-Kaloustian. Project administration: Charles B. Holmes, Elizabeth Bukusi, Andrew Kambugu, Craig Cohen, Carolyn Williams, Lameck Diero, Nancy Padian

Role of the US President's Emergency Plan for AIDS Relief in Responding to Tuberculosis and HIV Coinfection

. Holmes Office of the US Global AIDS Coordinator US President's Emergency Plan for AIDS Relief Washington DC The intersection of tuberculosis (TB) and human immunodeficiency virus (HIV) infection has

Global Pharmacovigilance for Antiretroviral Drugs: Overcoming Contrasting Priorities

Jur Strobos and colleagues describe the deliberations of a recent multi-stakeholder meeting discussing the creation of a sustainable global pharmacovigilance system for antiretroviral drugs that would be applicable in resource limited settings.

Optimizing Treatment for HIV-Infected South African Women Exposed to Single-Dose Nevirapine: Balancing Efficacy and Cost

Introduction. Nevirapine (NVP) resistance may decrease the effectiveness of viral suppression with NVP-based antiretroviral therapy (ART) in women infected with human immunodeficiency virus (HIV) with previous exposure to single-dose NVP. However, the alternative lopinavir-ritonavir—based ART regimen is more expensive. Our objectives were to project the tradeoffs regarding life ...

Expanding ART for Treatment and Prevention of HIV in South Africa: Estimated Cost and Cost-Effectiveness 2011-2050

Background Antiretroviral Treatment (ART) significantly reduces HIV transmission. We conducted a cost-effectiveness analysis of the impact of expanded ART in South Africa. Methods We model a best case scenario of 90% annual HIV testing coverage in adults 15–49 years old and four ART eligibility scenarios: CD4 count <200 cells/mm3 (current practice), CD4 count <350, CD4 count <500, ...

Review of Human Immunodeficiency Virus Type 1-Related Opportunistic Infections in Sub-Saharan Africa

Understanding the natural history of human immunodeficiency virus type 1 (HIV-1) and opportunistic infections in sub-Saharan Africa is necessary to optimize strategies for the prophylaxis and treatment of opportunistic infections and to understand the likely impact of antiretroviral therapy. We undertook a systematic review of the literature on HIV-1 infection in sub-Saharan Africa ...