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Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA

A recent study found that CD177 served as a receptor of membrane-bound proteinase-3 (mPR3) in a subset of neutrophils. Furthermore, CD177 has been identified as a high-affinity heterophilic binding partner for the endothelial cell platelet endothelial cell adhesion molecule-1 (PECAM-1). The current study aimed to investigate whether the interaction between PECAM-1 and CD177 could...

Hematocrit and the incidence of stroke: a prospective, population-based cohort study

Hematocrit and the incidence of stroke: a prospective, population-based cohort study Renling Yang,1,2 Anxin Wang,3–6 Li Ma,2 Zhaoping Su,7 Shuohua Chen,8 Yilong Wang,3–6 Shouling Wu,8 Chen Wang1,2 1Department of General Practice, School of General Practice and Continuing Education, Capital Medical University, Beijing, China; 2Department of General Practice, Beijing Tiantan...

Cylindricity Error Evaluation Based on an Improved Harmony Search Algorithm

The cylindricity error is one of the basic form errors in mechanical parts, which greatly influences the assembly accuracy and service life of relevant parts. For the minimum zone method (MZM) in international standards, there is no specific formula to calculate the cylindricity error. Therefore, the evaluation methods of the cylindricity error under the MZM have been widely...

LANTHANUM ELEMENT INDUCED IMBALANCE OF MINERAL NUTRIENTS, HSP 70 PRODUCTION AND DNA-PROTEIN CROSSLINK, LEADING TO HORMETIC RESPONSE OF CELL CYCLE PROGRESSION IN ROOT TIPS OF VICIA FABA L. SEEDLINGS

ROOT TIPS OF VICIA FABA L. SEEDLINGS Authors Chengrun Wany, Cuie Shi, Ling Liu, Chen Wang, Wei Qiao, Zhimang Gu, and Xiaorong Wang This article is available in Dose-Response: An International Journal

Is exclusion of leukocytes from platelet-rich plasma (PRP) a better choice for early intervertebral disc regeneration?

BackgroundPlatelet-rich plasma (PRP) is becoming a promising strategy to treat early intervertebral disc degeneration (IDD) in clinics. Pure PRP without leukocytes (P-PRP) may decrease the catabolic and inflammatory changes in the early degenerated intervertebral discs. The aim of this study was to investigate the effects of P-PRP on nucleus pulposus-derived stem cells (NPSCs...

DPP-4 Inhibitor Sitagliptin Improves Cardiac Function and Glucose Homeostasis and Ameliorates β-Cell Dysfunction Together with Reducing S6K1 Activation and IRS-1 and IRS-2 Degradation in Obesity Female Mice

Female Mice Shigang Qiao,1,2,3 Guofang Mao,4 Hua Li,2 Zhimin Ma,4 Lei Hong,1 Huiling Zhang,3 Chen Wang,1,2 and Jianzhong An1 1Institute of Clinical Medicine Research, The Affiliated Suzhou Hospital of ... Hospital, No. 1 Lijiang Road, Suzhou 215153, China Correspondence should be addressed to Chen Wang; moc.621@cw_yycjkzs and Jianzhong An; moc.621@zja_yycjkzs Received 9 April 2018; Revised 8 June 2018

Acute Physiological and Psychological Effects of Qigong Exercise in Older Practitioners

. Tze-Taur Wei, Chen-Chen Wang, WanChen Chen, and Yu-Min Wang participated in the literature searches and contributed to data collection of the study. Song-Yen Tsai contributed to revisions and the final

Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration

transferase dUTP nick end labeling; WISH, wholemount in situ hybridization. COMPLIANCE WITH ETHICS GUIDELINES Xiao-Shuai Han, Chen Wang, Fang-hao Guo, Shuang Huang, YongWen Qin, Xian-Xian Zhao and Qing Jing

Taking the Sector Seriously: Data, Developments, and Drivers of Intrasectoral Earnings Inequality

The widespread increase in earnings inequality within postindustrial countries has received a lot of attention in both the public debate and the academic literature. Remarkably, the developments in earnings inequality have mainly been studied at the country level, whereas there is substantial variation across sectors within countries. This study explores the developments and the...

Unraveling the roles of CD44/CD24 and ALDH1 as cancer stem cell markers in tumorigenesis and metastasis

Chen Wang YanlianYang OPEN CD44/CD24 and ALDH1 are widely used cancer stem cell (CSC) markers in breast cancer. However, their expression is not always consistent even in the same subtype of breast

Structural basis of antifreeze activity of a bacterial multi-domain antifreeze protein

at beamline X6A. Author Contributions Conceptualization: Bing-Hao Luo. Investigation: Chen Wang. Methodology: Chen Wang. Supervision: Bing-Hao Luo. Data curation: Chen Wang, Svetlana Pakhomova ... , Marcia E. Newcomer, Brent C. Christner. Formal analysis: Chen Wang, Svetlana Pakhomova, Brent C. Christner, Bing-Hao Luo. Validation: Marcia E. Newcomer, Brent C. Christner, Bing-Hao Luo. 16 / 19 12

A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity

: Romain Cartoni, Thomas L. Schwarz, Zhigang He. Methodology: Romain Cartoni. Resources: Chen Wang. Software: Gulcin Pekkurnaz. Supervision: Thomas L. Schwarz, Zhigang He. Writing ± original draft

Quantitative thyroglobulin response to radioactive iodine treatment in predicting radioactive iodine-refractory thyroid cancer with pulmonary metastasis

: Chen Wang, Yansong Lin. Data curation: Chen Wang, Xin Zhang. Formal analysis: Chen Wang, Xin Zhang. Funding acquisition: Yansong Lin. Methodology: Xin Zhang, Hui Li, Xin Li. Project administration ... : Hui Li, Xin Li. Resources: Chen Wang, Xin Li. Software: Hui Li, Xin Li. Supervision: Xin Li. Validation: Xin Zhang, Hui Li. Visualization: Chen Wang, Hui Li. Writing ± original draft: Chen Wang

Novel strategy of stents in thyroid mass: a case series report of managing severely dyspneic patients

Novel strategy of stents in thyroid mass: a case series report of managing severely dyspneic patients Adheesh Bhandari,* Ying-hao Wang,* Shi-xu Lv, Er-jie Xia, Ou-Chen Wang Department of Oncology

IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury

• PubMed • Google Scholar Search for Lo-Hsin Dai in:Nature Research journals • PubMed • Google Scholar Search for Wan-Chen Wang in:Nature Research journals • PubMed • Google Scholar Search for Ya-Jen

Effects of minor Y, Zr and Er addition on microstructure and properties of Al-5Cu-0.4Mn alloy

The effect of different contents of Y, Zr and Er on microstructure and properties of Al-5Cu-0.4Mn alloy was investigated. T6 heat treatment, OM, SEM and EDS methods were applied to the alloy. The results showed that fluidity and elongation of alloy adding Y, Zr and Er were improved, while with the increase of addition amounts, θ phase increased and grains were trended to grow up...

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing

and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USADavid C. Marciano, Chen Wang, Christophe Herman & Olivier LichtargeQuantitative and Computational Biosciences, Baylor College of ... for Benu Atri in:Nature Research journals • PubMed • Google Scholar Search for Rachel E. Bosserman in:Nature Research journals • PubMed • Google Scholar Search for Chen Wang in:Nature Research

Prognostic value of thyroid hormones in acute ischemic stroke – a meta analysis

Ji Wang Chen Wang Yan Wu OPEN Published: xx xx xxxx Previous studies on the association between thyroid hormones and prognosis of acute ischemic stroke (AIS) reported conflicting results. We

FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of miR-322-5p

The proliferation and migration of vascular smooth muscle cells (VSMCs) play an essential role during the development of cardiovascular diseases (CVDs). While many factors potentially contribute to the abnormal activation of VSMCs, hyperglycemia is generally believed to be a major causative factor. On the other hand, FAM3B (named PANDER for its secretory form) is a uniquely...