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14 papers found.
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Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo

Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo Jiayang He,1 Ping Fang,2 Xiang Zheng,2 Chenchen Wang,2 Tenghui Liu,2 Bowen Zhang,2 Jian Wen,2 Ren-ai Xu3 1Department of

Speciation determination of iron and its spatial and seasonal distribution in coastal river

• Google Scholar Search for Mingyue Lin in:Nature Research journals • PubMed • Google Scholar Search for Yan Lu in:Nature Research journals • PubMed • Google Scholar Search for Chenchen Wang in:Nature

Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation

Embryonic stem cells (ESCs) are pluripotent cells and have the capability for differentiation into any of the three embryonic germ layers. The Wnt/β-Catenin pathway has been shown to play an essential role in ESC differentiation regulation. Activation of β-Catenin by post-translational modification has been extensively studied. However, mechanism(s) of post-transcriptional...

Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation

 Chenchen Wang,4 Yuan Han,5 Chao Song,6 Xueming Hu,7 and Yannan Liu8 1Department of Anesthesiology, Xuzhou Cancer Hospital, Affiliated Xuzhou Hospital, Jiangsu University, Xuzhou 221005, China 2Jiangsu ... interpreted results; Chenchen Wang performed the experiments and wrote the paper; Yuan Han contributed significantly to paper preparation; Chao Song helped perform the analysis with constructive discussions

Can alcohol consumption be an alternative treatment for fibromyalgia?

Treatment of chronic pain conditions such as fibromyalgia is challenging due to limitations of drug therapies. An initial exploration into the relationships between self-reported alcohol consumption, symptom severity, and quality of life for individuals with fibromyalgia sheds new light on plausible hypotheses and potential mechanisms of action for future research. Evidence...

Chinese Herbal Bath Therapy for the Treatment of Knee Osteoarthritis: Meta-Analysis of Randomized Controlled Trials

authors were involved in drafting the paper or revising it critically for important intellectual content, and all authors approved the final version to be published. Chenchen Wang and Bo Chen designed the

The Effects of Mind-Body Therapies on the Immune System: Meta-Analysis

Importance Psychological and health-restorative benefits of mind-body therapies have been investigated, but their impact on the immune system remain less defined. Objective To conduct the first comprehensive review of available controlled trial evidence to evaluate the effects of mind-body therapies on the immune system, focusing on markers of inflammation and anti-viral related...

Association between TLR4 (+896A/G and +1196C/T) Polymorphisms and Gastric Cancer Risk: An Updated Meta-Analysis

Background Toll-like receptor 4 (TLR4) is a receptor of lipopolysaccharide in the signaling transduction of gastric epithelial cell. It plays a pivotal role in activation of innate immunity and pathogen recognition and thus acts as a modulator in the development and progression of gastric cancer. Growing studies explored the association of polymorphisms in TLR4 with...

Accelerating materials property predictions using machine learning

06269Ghanshyam Pilania, Chenchen Wang & Ramamurthy RamprasadDepartment of Statistics, University of Connecticut, 215 Glenbrook Road, Storrs, Connecticut 06269Xun JiangDepartment of Computer Science and Engineering ... , University of Connecticut, 371 Fairfield Road, Storrs, Connecticut 06269Sanguthevar Rajasekaran AuthorsSearch for Ghanshyam Pilania in:Nature Research journals • PubMed • Google ScholarSearch for Chenchen Wang

A novel comparative effectiveness study of Tai Chi versus aerobic exercise for fibromyalgia: study protocol for a randomized controlled trial

Background Fibromyalgia is a chronic musculoskeletal pain syndrome that causes substantial physical and psychological impairment and costs the US healthcare system over $25 billion annually. Current pharmacological therapies may cause serious adverse effects, are expensive, and fail to effectively improve pain and function. Finding new and effective non-pharmacological treatments...

The Increased Effectiveness of HIV Preventive Intervention among Men Who Have Sex with Men and of Follow-Up Care for People Living with HIV after ‘Task-Shifting’ to Community-Based Organizations: A ‘Cash on Service Delivery’ Model in China

Background A large number of men who have sex with men (MSM) and people living with HIV/AIDS (PLHA) are underserved despite increased service availability from government facilities while many community based organizations (CBOs) are not involved. We aimed to assess the feasibility and effectiveness of the task shifting from government facilities to CBOs in China. Methods HIV...

Measuring and Valuing Health-Related Quality of Life among Children and Adolescents in Mainland China – A Pilot Study

Background The Child Health Utility 9D (CHU9D), a new generic preference-based health-related quality of life (HRQoL) instrument, has been validated for use in young people in both the UK and Australia. The main objectives of this study were to examine the feasibility of using a Chinese version of the CHU9D (CHU9D-CHN) to assess HRQoL and to investigate the association of...

Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans

treatment in Kazakans Weili Yan Yuanming Zhang Zimei Shan Qian Wang Yongdi Huang Chenchen Wang Kai Yan Hypothesis: Polymorphisms of REN, AGTR1 and AGTR2 may be associated with responses of renin

The Combination of RAD001 and MK-2206 Exerts Synergistic Cytotoxic Effects against PTEN Mutant Gastric Cancer Cells: Involvement of MAPK-Dependent Autophagic, but Not Apoptotic Cell Death Pathway

In the current study, we showed that the combination of mammalian target of rapamycin (mTOR) inhibitor RAD001 (everolimus) and Akt inhibitor MK-2206 exerted synergistic cytotoxic effects against low-phosphatase and tensin homolog (PTEN) gastric cancer cells (HGC-27 and SNU-601 lines). In HGC-27 cells, RAD001 and MK-2206 synergistically induced G1/S cell cycle arrest, growth...