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Association between age at onset of independent walking and objectively measured sedentary behavior is mediated by moderate-to-vigorous physical activity in primary school children

National Institute of Health and Nutrition for their help with the survey. Author Contributions Conceptualization: Tomoko Aoyama, Maki Tanaka, Masayuki Okuda, Shigeru Inoue, Chiaki Tanaka. Data curation ... : Tomoko Aoyama, Maki Tanaka. Formal analysis: Tomoko Aoyama. Funding acquisition: Tomoko Aoyama, Chiaki Tanaka. Investigation: Tomoko Aoyama, Maki Tanaka, Chiaki Tanaka. Methodology: Shigeho Tanaka

Association between objectively evaluated physical activity and sedentary behavior and screen time in primary school children

Background Even when meeting guidelines for physical activity (PA), considerable sedentary time may be included. This study in primary school children investigated the relationships between objectively evaluated sedentary and PA times at different intensities using triaxial accelerometry that discriminated between ambulatory and non-ambulatory PA. The relationships between...

Seasonal changes in objectively measured sedentary behavior and physical activity in Japanese primary school children

Background The recent prevalence of obesity in Japanese children is much higher compared to 1980. The present study compared daily sedentary behavior (SB) and physical activity (PA) between the school year and summer vacation in Japanese primary school children. Methods Participants were 98 Japanese boys (8.9 ± 1.8 years at baseline) and 111 girls (9.1 ± 1.8 years). SB and PA...

Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies

The homeobox protein, PEPP2 (RHOXF2), has been suggested as a cancer/testis (CT) antigen based on its expression pattern. However, the peptide epitope of PEPP2 that is recognized by cytotoxic T cells (CTLs) is unknown. In this study, we revealed that PEPP2 gene was highly expressed in myeloid leukemia cells and some other hematological malignancies. This gene was also expressed...

Developmental Changes in the Corpus Callosum from Infancy to Early Adulthood: A Structural Magnetic Resonance Imaging Study

Previous research has reported on the development trajectory of the corpus callosum morphology. However, there have been only a few studies that have included data on infants. The goal of the present study was to examine the morphology of the corpus callosum in healthy participants of both sexes, from infancy to early adulthood. We sought to characterize normal development of the...

Gender Differences in Metabolic Responses During Water Walking

Ohgi are with the Graduate School of Media and Governance at Keio University in Fujisawa, Japan. Chiaki Tanaka is with J.F. Oberlin University, College of Health and Welfare in Machida, Japan. 1 422

Prediction Models Discriminating between Nonlocomotive and Locomotive Activities in Children Using a Triaxial Accelerometer with a Gravity-removal Physical Activity Classification Algorithm

The aims of our study were to examine whether a gravity-removal physical activity classification algorithm (GRPACA) is applicable for discrimination between nonlocomotive and locomotive activities for various physical activities (PAs) of children and to prove that this approach improves the estimation accuracy of a prediction model for children using an accelerometer. Japanese...

Developmental Trajectories of Amygdala and Hippocampus from Infancy to Early Adulthood in Healthy Individuals

Knowledge of amygdalar and hippocampal development as they pertain to sex differences and laterality would help to understand not only brain development but also the relationship between brain volume and brain functions. However, few studies investigated development of these two regions, especially during infancy. The purpose of this study was to examine typical volumetric...