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A Proteomic Approach for the Diagnosis of ‘Oketsu’ (blood stasis), a Pathophysiologic Concept of Japanese Traditional (Kampo) Medicine

‘Oketsu’ is a pathophysiologic concept in Japanese traditional (Kampo) medicine, primarily denoting blood stasis/stagnant syndrome. Here we have explored plasma protein biomarkers and/or diagnostic algorithms for ‘Oketsu’. Sixteen rheumatoid arthritis (RA) patients were treated with keishibukuryogan (KBG), a representative Kampo medicine for improving ‘Oketsu’. Plasma samples...

Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation

stress exist. (TIF) Author Contributions Conceptualization: Chinami Matsumoto, Chihiro Yamada, Chiharu Sadakane, Tomohisa Hattori, Hiroshi Takeda. Data curation: Chinami Matsumoto, Chihiro Yamada ... , Chiharu Sadakane, Tomohisa Hattori. Formal analysis: Chinami Matsumoto, Chihiro Yamada, Chiharu Sadakane, Miwa Nahata, Tomohisa Hattori. Funding acquisition: Chinami Matsumoto, Chihiro Yamada, Chiharu

Analysis of the antioxidative function of the radioprotective Japanese traditional (Kampo) medicine, hangeshashinto, in an aqueous phase

The authors report no conflicts of interest. Financial support for this study was provided by Tsumura & Co. Chinami Matsumoto, Yuji Omiya, Yoshio Kase and Masato Fukutake are employees of Tsumura & Co