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Daily circadian misalignment impairs human cognitive performance task-dependently

from the National Center for Research Resources). Author information Author notes Sarah L. Chellappa and Christopher J. Morris contributed equally to this work. AffiliationsMedical Chronobiology ... Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital, Boston, MA, 02115, United StatesSarah L. Chellappa, Christopher J. Morris & Frank A

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue

Purpose Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers. Methods Anionic PAMAM dendrimers and control dextran probes were applied to an isolated perfused rat...