BackgroundSeveral professional contact and collision sports have recently introduced the use of sideline video review for club medical staff to help identify and manage concussions. As such, reviewing video footage on the sideline has become increasingly relied upon to assist with improving the identification of possible injury. However, as yet, a standardized method for...
Md Golam Hasnain, Christine L. Paul, John R. Attia, Annika Ryan, Catherine A. D’Este, Isobel J. Hubbard & Christopher R. Levi Hunter Medical Research Institute (HMRI), New Lambton Heights, Australia ... Abul Hasnat Milton The Sydney Partnership for Health, Education, Research & Enterprise (SPHERE), Sydney, Australia Christopher R. Levi AuthorsMd Golam Hasnain View author publications You can also
Introduction: The incidence of pituitary dysfunction after severe ischemic stroke is unknown, however given the increasing attention to pituitary dysfunction after neurological injuries such as traumatic brain injury, this may represent a novel area of research in stroke.Methods: We perform an arginine and human growth hormone releasing hormone challenge on ischemic stroke...
R. Levi 0 3 Grant L. Iverson 4 5 9 0 Centre for Stroke and Brain Injury, School of Medicine and Public Health, University of Newcastle , Callaghan , Australia 1 Priority Research Centre for Stroke and
Tissue plasminogen activator (tPA) is the only approved thrombolytic therapy for acute ischemic stroke, yet many patients do not recanalize. Enhancing thrombolytic efficacy of tPA is a major focus of stroke research. Traditionally, a “rat dose” of 10 mg/kg has been used in rodent models. Recent studies suggested that the clinical “human” dose (0.9 mg/kg) may better mimic clinical...
Background Emergency department staff play a crucial role in the triage of stroke patients and therefore the capacity to deliver time-dependent treatments such as tissue Plasminogen Activator. This study aimed to identify among emergency physicians, (1) rates of agreement with evidence supporting tissue Plasminogen Activator use in acute stroke care; and (2) individual and...
Craniocervical arterial dissection is a major cause of ischaemic stroke in young adults. The pathogenesis is not fully understood but is thought to be related to a combination of an intrinsic weakness in the arterial wall and an external trigger. Intrinsic susceptibility is thought to be a generalised arteriopathy, vascular anomaly or genetic predisposition. Proposed extrinsic...
Background Many aspects of CSF dynamics are poorly understood due to the difficulties involved in quantification and visualization. In particular, there is debate surrounding the route of CSF drainage. Our aim was to quantify CSF flow, volume, and drainage route dynamics in vivo in young and aged spontaneously hypertensive rats (SHR) using a novel contrast-enhanced computed...
Intraluminal occlusion of the middle cerebral artery (MCAo) in rodents is perhaps the most widely used model of stroke, however variability of infarct volume and the ramifications of this on sample sizes remains a problem, particularly for preclinical testing of potential therapeutics. Our data and that of others, has shown a dichotomous distribution of infarct volumes for which...
Background Stroke is a leading cause of death and disability internationally. One of the three effective interventions in the acute phase of stroke care is thrombolytic therapy with tissue plasminogen activator (tPA), if given within 4.5 hours of onset to appropriate cases of ischaemic stroke. Objectives To test the effectiveness of a multi-component multidisciplinary...
. Parsons 14 15 18 Teddy Y. Wu 8 15 18 Mark Brooks 15 16 18 Marion A. Simpson 15 16 18 Ferdinand Miteff 14 15 17 18 Christopher R. Levi 14 15 18 Martin Krause 15 18 19 Timothy J. Harrington 15 17 18 Kenneth C
