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6 papers found.
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Optimal timing of blastocyst vitrification after trophectoderm biopsy for preimplantation genetic screening

, Chun-Chia Huang, Tsung-Hsien Lee. Data curation: Hsiu-Hui Chen, Lee-Feng Chien. Formal analysis: Hsiu-Hui Chen. Funding acquisition: Maw-Sheng Lee. Methodology: Hsiu-Hui Chen, Chun-Chia Huang, En-Hui ... Cheng. Project administration: Chun-Chia Huang, Maw-Sheng Lee. Resources: En-Hui Cheng, Maw-Sheng Lee. Supervision: Maw-Sheng Lee. Writing ± original draft: Hsiu-Hui Chen. Writing ± review & editing

Requirement of Leukemia Inhibitory Factor or Epidermal Growth Factor for Pre-Implantation Embryogenesis via JAK/STAT3 Signaling Pathways

Leukemia inhibitory factor (LIF) plays a key role in the survivability of mouse embryos during pre-implantation. In this study, we verified the role of LIF by detecting gene expression in morula stage embryos through DNA microarray. Our results showed that LIF knockdown affected expression of 369 genes. After LIF supplementation, the epidermal growth factor (EGF) is most affected...

Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo quality†

STUDY QUESTION Is the relative telomere length in cumulus cells associated with embryo quality and the subject's age?

Impact of female age and male infertility on ovarian reserve markers to predict outcome of assisted reproduction technology cycles

Background This study was designed to assess the capability of ovarian reserve markers, including baseline FSH levels, baseline anti-Müllerian hormone (AMH) levels, and antral follicle count (AFC), as predictors of live births during IVF cycles, especially for infertile couples with advanced maternal age and/or male factors. Methods A prospective cohort of 336 first IVF/ICSI...

Magnetic-activated cell sorting for sperm preparation reduces spermatozoa with apoptotic markers and improves the acrosome reaction in couples with unexplained infertility†

BACKGROUND Couples with unexplained infertility (UI) tend to have low fertilization rates with current IVF procedures. Here, we attempted to identify spermatozoa with apoptotic markers in couples with UI and unsuccessful intrauterine insemination (IUI) and we investigated the efficiency and benefit of magnetic-activated cell sorting (MACS) for sperm preparation in such patients...

Successful pregnancy following blastocyst cryopreservation using super-cooling ultra-rapid vitrification

BACKGROUND: Blastocysts were cryopreserved by a new two-step ultra-rapid cooling in super-cooled liquid nitrogen (−205°C). METHODS: There were 308 mouse blastocysts collected from fertile B6CBF1 mice and 249 human blastocysts collected from 51 couples treated with IVF. The blastocysts were super-cooled by a Vit-Master™ and cryoloops after treatment in 50 and 100% vitrification...