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Search: authors:"Climente-González, Héctor"

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FoldX accurate structural protein–DNA binding prediction using PADA1 (Protein Assisted DNA Assembly 1)

The speed at which new genomes are being sequenced highlights the need for genome-wide methods capable of predicting protein–DNA interactions. Here, we present PADA1, a generic algorithm that accurately models structural complexes and predicts the DNA-binding regions of resolved protein structures. PADA1 relies on a library of protein and double-stranded DNA fragment pairs...