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Reduced inattention and hyperactivity and improved cognition after marine oil extract (PCSO-524®) supplementation in children and adolescents with clinical and subclinical symptoms of attention-deficit hyperactivity disorder (ADHD): a randomised, double-blind, placebo-controlled trial

Introduction This study investigated the effects of a marine oil extract (PCSO-524®) on inattention, hyperactivity, mood and cognition in children and adolescents. PCSO-524® is a standardised lipid extract of the New Zealand green-lipped mussel and is an inflammatory modulator that inhibits the 5′-lipoxygenase and cyclooxygenase pathways and decreases concentrations of the ...

Reduced inattention and hyperactivity and improved cognition after marine oil extract (PCSO-524®) supplementation in children and adolescents with clinical and subclinical symptoms of attention-deficit hyperactivity disorder (ADHD): a randomised, double-blind, placebo-controlled trial

Introduction This study investigated the effects of a marine oil extract (PCSO-524®) on inattention, hyperactivity, mood and cognition in children and adolescents. PCSO-524® is a standardised lipid extract of the New Zealand green-lipped mussel and is an inflammatory modulator that inhibits the 5′-lipoxygenase and cyclooxygenase pathways and decreases concentrations of the ...

Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial

Background Generalised anxiety disorder (GAD) is a chronic and pervasive condition that generates high levels of psychological stress, and it is difficult to treat in the long term. Current pharmacotherapeutic options for GAD are in some cases only modestly effective, and may elicit undesirable side effects. Through targeted actions on the gamma-aminobutyric acid (GABA) pathway, ...

Reducing occupational stress with a B-vitamin focussed intervention: a randomized clinical trial: study protocol

Background Workplace stress in Australia and other western countries has been steadily increasing over the past decade. It can be observed not only in terms of increased compensation claims but also costs due to absenteeism, loss of productivity at work and reduced psychological and physiological health and well-being. Given the cost and pervasive effects of stress in the modern ...

A Randomised Placebo-Controlled Trial to Differentiate the Acute Cognitive and Mood Effects of Chlorogenic Acid from Decaffeinated Coffee

process, also warrants further investigation. The data for the current study is freely available on request by contacting the corresponding author Prof Con Stough: . Supporting Information

A randomized controlled trial investigating the effects of PCSO-524®, a patented oil extract of the New Zealand green lipped mussel (Perna canaliculus), on the behaviour, mood, cognition and neurophysiology of children and adolescents (aged 6–14 years) experiencing clinical and sub-clinical levels of hyperactivity and inattention: study protocol ACTRN12610000978066

Background The prevalence rate of attention-deficit/hyperactivity disorder (ADHD) within Western cultures is between 5% and 12%, and is the most common psychiatric illness among school-aged children, with an estimated 50% of these children retaining ADHD symptoms for the rest of their lives. Children with ADHD have lower blood levels of long-chain Poly Unsaturated Fatty Acids (LC ...

Participant experiences from chronic administration of a multivitamin versus placebo on subjective health and wellbeing: a double-blind qualitative analysis of a randomised controlled trial

Background While many randomised controlled trials have been conducted on multivitamins, to our knowledge no qualitative research exploring the subjective experience of taking a multivitamin during a clinical trial has been reported. Methods Semi-structured and open-ended written questions were incorporated into a 16-week double-blind, randomised, placebo-controlled, parallel ...

Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study

Andrew Scholey Anastasia Ossoukhova Lauren Owen Alvin Ibarra Andrew Pipingas Kan He Marc Roller Con Stough Rationale Over the last decade, Asian ginseng (Panax ginseng) has been shown to improve

ALCOHOL IMPAIRS SPEED OF INFORMATION PROCESSING AND SIMPLE AND CHOICE REACTION TIME AND DIFFERENTIALLY IMPAIRS HIGHER-ORDER COGNITIVE ABILITIES

KATHERINE TZAMBAZIS 0 CON STOUGH 0 0 Brain Sciences Institute, Swinburne University of Technology , P.O. Box 218, Hawthorn, Victoria, 3122, Australia Previous research has demonstrated that alcohol

A delivery system for olfactory stimuli

This paper describes the design of a new method for controlling and administering olfactory stimuli—namely, thehood system. The hood system involves a stream of vaporized odor (at known concentrations) mixed with odorless air and pumped (at a constant flow rate) into an oxygen therapy hood. It is designed to be used with odorants in solution, such as essential oils, as the ...