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Room escape at class: Escape games activities to facilitate the motivation and learning in computer science

Journal of Technology and Science Education JOTSE 2013-6374 ESCAPE AT CLASS: ESCAPE GAMES ACTIVITIES TO FACILITATE THE MOTIVATION AND LEARNING IN COMPUTER SCIENCE Carlos Borrego 0 Cristina

Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies

Mas receptor (MasR) is a G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang (1–7) protective axis of renin–angiotensin system. Because the role of this receptor is not definitively clarified, determination of MasR tissue distribution and expression levels constitutes a critical knowledge to fully understanding its...

Obesity and Cardiovascular Risk: Variations in Visfatin Gene Can Modify the Obesity Associated Cardiovascular Risk. Results from the Segovia Population Based-Study. Spain

Objectives Our aim was to investigate if genetic variations in the visfatin gene (SNPs rs7789066/ rs11977021/rs4730153) could modify the cardiovascular-risk (CV-risk) despite the metabolic phenotype (obesity and glucose tolerance). In addition, we investigated the relationship between insulin sensitivity and variations in visfatin gene. Material and Methods A population-based...

Fourier domain optical coherence tomography to assess the iridocorneal angle and correlation study in a large Caucasian population

Background Recently, novel anatomic parameters that can be measured by optical coherence tomography (OCT), have been identified as a more objective and accurate method of defining the iridocorneal angle. The aim of the present study is to measure the iridocorneal angle by Fourier domain (FD) OCT and to identify correlations between angle measurements and subject factors in a...

Differential Gene Susceptibility to Sperm DNA Damage: Analysis of Developmental Key Genes in Trout

Sperm chromatin in mammals is packaged in different blocks associated to protamines (PDNA), histones (HDNA), or nuclear matrix proteins. Differential packaging has been related to early or late transcription and also to differential susceptibility to genotoxic damage. Genes located in the more accessible HDNA could be more susceptible to injuries than those located in PDNA, being...

The impact of bariatric surgery on renal and cardiac functions in morbidly obese patients

Background Cardiac adaptation to obesity includes both structural and functional alterations in the heart. The kidneys also suffer the consequence of excessive increase of body weight. This study aims to assess the functional, cardiac and renal changes in a cohort of morbidly obese patients, as well as changes after bariatric surgery–the last therapeutic option for these patients.

Is pre-commercial thinning compatible with carbon sequestration? A case study in a maritime pine stand in northwestern Spain

The mid-term effects on carbon sequestration of two consecutive pre-commercial thinnings with different intensities were analysed in a heavily stocked Pinus pinaster Ait. stand in northwestern Spain. Thinning was carried out 5 and 8 years after seedling establishment. Intense thinning reduced the initial sapling density by 92 per cent after the first treatment and by 87 per cent...

Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

IntroductionAsthma Control Questionnaire (ACQ) is a validated tool to measure asthma control. Cut-off points that best discriminate “well-controlled” or “not well-controlled” asthma have been suggested from the analysis of a large randomized clinical trial but they may not be adequate for daily clinical practice.AimsTo establish cut-off points of the ACQ that best discriminate...

Influence of Vitamin D-Related Gene Polymorphisms (CYP27B and VDR) on the Response to Interferon/Ribavirin Therapy in Chronic Hepatitis C

Background and Aims Vitamin D exerts immunomodulatory effects on the host response against infection with hepatitis C virus (HCV). This study was performed to assess the putative influence of polymorphisms in vitamin D-related genes on the response to antiviral therapy in patients with chronic hepatitis C (CHC). Methods Single nucleotide polymorphisms (SNPs) in CYP27B-1260 gene...

Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results

Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results Cristina Fernández-Fernández,1 Luis F Callado,2 Rocío Girón,3 Eva Sánchez,3 Amaia M Erdozain,2 José

Protective effect of rifampicin and clindamycin impregnated devices against Staphylococcus spp. infection after cerebrospinal fluid diversion procedures

Background Infection is a major complication of cerebrospinal fluid shunting procedures. The present report assesses the efficacy of such catheters in both shunts and external ventricular drains (EVDs) against infection and particularly against Staphylococcus spp. infection. Methods All shunt and EVD procedures performed by means of antibiotic-impregnated catheters (AICs) and non...

Nitrogen mineralization after clearcutting and residue managementin a second rotation Eucalyptus globulus Labill. stand in Galicia (NW Spain)

• The effects of clearcutting and of different slash management procedures on N mineralization were assessed in a Eucalyptus globulus Labill. stand in Galicia (N W Spain). Treatments were no clearcutting (control), clearcutting combined with scattering, scattering + fertilization, windrowing, and two types of slash burning with two levels of severity: broadcast burning and...

Serum level of fibroblast growth factor 23 in maintenance renal transplant patients

Background The discovery of fibroblast growth factor 23 (FGF23) provides a new conceptual framework that improves our understanding of the pathogenesis of post-transplant bone disease. Excess FGF23 is produced in the early post-transplant period; levels return to normal in the months following transplant. However, few manuscripts discuss FGF23 levels in stable long-term renal...

Target organ damage and cardiovascular complications in patients with hypertension and type 2 diabetes in Spain: a cross-sectional study

Background Target organ damage (mainly cardiac and renal damage) is easy to evaluate in outpatient clinics and offers valuable information about patient's cardiovascular risk. The purpose of this study was to evaluate, using simple methods, the prevalence of cardiac and renal damage and its relationship to the presence of established cardiovascular disease (CVD), in patients with...

Association between phosphate removal and markers of bone turnover in haemodialysis patients

Background. As the main mineral reservoir, bone acts as a calcium (Ca) and phosphate buffering system. Accordingly, phosphate removal by haemodialysis (HD) might be theoretically influenced by bone turnover, as well as by the interaction of regulatory molecules, such as PTH and osteoprotegerin (OPG). The present study investigated the relationship between these variables and...

Vessel Shrinkage as a Sign of Atherosclerosis Progression in Type 2 Diabetes: A Serial Intravascular Ultrasound Analysis

OBJECTIVE—The aim of this study was to determine the natural history of vascular remodeling of atherosclerotic plaques in patients with type 2 diabetes and the predictors of vessel shrinkage. RESEARCH DESIGN AND METHODS—In this serial intracoronary ultrasound (IVUS) study, 237 coronary segments from 45 patients enrolled in the DIABETES I, II, and III trials were included...

Nosocomial Outbreak of Burkholderia pickettii Infection Due to a Manufactured Intravenous Product Used in Three Hospitals

Forty-six cases of nosocomial infection caused by Burkholderia pickettii were reported between June and November 1993 in three metropolitan hospitals in Madrid. A case-control study of the outbreak was conducted to identify its cause. Seventy-four percent of the patients were males; the mean age ± SD of the patients was 54 ± 20 years. Sixty-five percent of the patients presented...