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Search: authors:"Crystal Dykstra"

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Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice

Background Humanized mouse models are an increasingly popular preclinical model to study the human immune response in a biological system. There are a variety of protocols to generate these mice, each differing in the strain of the recipient, source of hematopoietic stem cells, and mode of transplantation. Though there is well-documented reconstitution information regarding the...