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Brain gray matter structural network in myotonic dystrophy type 1

Sone, Hiroshi Matsuda. Investigation: Atsuhiko Sugiyama. Methodology: Daichi Sone, Yukio Kimura, Miho Ota, Norihide Maikusa, Satoshi Kuwabara. Project administration: Atsuhiko Sugiyama, Daichi Sone ... Conceptualization: Atsuhiko Sugiyama, Madoka Mori-Yoshimura, Yasushi Ohya. 10 / 13 Data curation: Yukio Kimura, Tomoko Maekawa, Mikako Enokizono, Madoka Mori Yoshimura. Formal analysis: Atsuhiko Sugiyama, Daichi

Validation of the cingulate island sign with optimized ratios for discriminating dementia with Lewy bodies from Alzheimer’s disease using brain perfusion SPECT

Objective Dementia with Lewy bodies (DLB) is often cited as the second most common dementia after Alzheimer’s disease (AD). It is clinically important to distinguish DLB from AD because specific side effects of antipsychotic drugs are limited to DLB. The relative preservation of cingulate glucose metabolism in the posterior cingulate gyri versus that in the precuni, known as the...

The cingulate island sign within early Alzheimer’s disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer’s disease from dementia with Lewy bodies

Background In addition to occipital hypoperfusion, preserved metabolism of the posterior cingulate gyri (PCG) relative to the precunei is known as the cingulate island sign (CIS) in the patients with dementia with Lewy bodies (DLB). CIS has been detected using [18F]fluorodeoxyglucose positron emission tomography but not using brain perfusion single-photon emission computed...

Graph Theoretical Analysis of Structural Neuroimaging in Temporal Lobe Epilepsy with and without Psychosis

Purpose Psychosis is one of the most important psychiatric comorbidities in temporal lobe epilepsy (TLE), and its pathophysiology still remains unsolved. We aimed to explore the connectivity differences of structural neuroimaging between TLE with and without psychosis using a graph theoretical analysis, which is an emerging mathematical method to investigate network connections...