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HIV incidence among sexual health clinic attendees in England: First estimates for black African heterosexuals using a biomarker, 2009-2013

days as the mean duration of recent infection (MDRI) for the assay (personal communication Daniela De Angelis). The coverage of testing for recent infection increased from 25% of all new HIV diagnoses ... , Daniela De Angelis, Valerie Delpech. Data curation: Adamma Aghaizu, Jennifer Tosswill, Gary Murphy. Formal analysis: Adamma Aghaizu, Daniela De Angelis. Methodology: Adamma Aghaizu, Helen Ward, Gary

Construction of the influenza A virus transmission tree in a college-based population: co-transmission and interactions between influenza A viruses

-Sheng Zhang 0 1 Daniela De Angelis 1 0 Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College School of Public Health

The Possible Impact of Vaccination for Seasonal Influenza on Emergence of Pandemic Influenza via Reassortment

Background One pathway through which pandemic influenza strains might emerge is reassortment from coinfection of different influenza A viruses. Seasonal influenza vaccines are designed to target the circulating strains, which intuitively decreases the prevalence of coinfection and the chance of pandemic emergence due to reassortment. However, individual-based analyses on 2009...

Recapture or Precapture? Fallibility of Standard Capture-Recapture Methods in the Presence of Referrals Between Sources

, Colindale, London, United Kingdom (Daniela De Angelis, Ross J. Harris); and Medical Research Council Biostatistics Unit, Cambridge, United Kingdom (Daniela De Angelis). This work was funded by the Medical

Risk of Pelvic Inflammatory Disease Following Chlamydia trachomatis Infection: Analysis of Prospective Studies With a Multistate Model

Medicine, University of Bristol, Bristol, United Kingdom (A. E. Ades, Nicky J. Welton, John Macleod, Katy Turner, Paddy J. Horner); Health Protection Agency, London, United Kingdom (Daniela De Angelis, Kate ... Soldan, Ian Simms); Medical Research Council Biostatistics Unit, Cambridge, United Kingdom (Daniela De Angelis); and Bristol Sexual Health Centre, University Hospital Bristol NHS Foundation Trust, Bristol

Estimating the Effectiveness of Isolation and Decolonization Measures in Reducing Transmission of Methicillin-resistant Staphylococcus aureus in Hospital General Wards

Biostatistics Unit, University of Cambridge , Cam- bridge , United Kingdom (Daniela De Angelis) ; Guy's Infection control for hospital pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) often

The Edinburgh Addiction Cohort: recruitment and follow-up of a primary care based sample of injection drug users and non drug-injecting controls

Background Injection drug use is an important public health problem. Epidemiological understanding of this problem is incomplete as longitudinal studies in the general population are difficult to undertake. In particular little is known about early life risk factors for later drug injection or about the life course of injection once established including the influence of medical...

Estimating Long-term Trends in the Incidence and Prevalence of Opiate Use/Injecting Drug Use and the Number of Former Users: Back-Calculation Methods and Opiate Overdose Deaths

The authors explored an age-specific back-calculation approach to estimating long-term trends in the incidence and prevalence of opiate use/injecting drug use (IDU) in England for 1968–2000. The incidence of opiate use/IDU was estimated by combining information on the observed opiate overdose deaths of persons aged 15–44 years with knowledge on the distribution of the time...

Hepatitis C Infection Among Injecting Drug Users in England and Wales (1992–2006): There and Back Again?

: Medical Research Council Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom (Michael J. Sweeting, Daniela De Angelis); Centre for Research on Drugs and Health Behaviour, Department ... . Hope, John V. Parry, Fortune Ncube, Mary E. Ramsay, Daniela De Angelis); and Department of Social Medicine, University of Bristol, Bristol, United Kingdom (Matthew Hickman). This work was supported by

Estimating the Relative Incidence of Heroin Use: Application of a Method for Adjusting Observed Reports of First Visits to Specialized Drug Treatment Agencies

In this paper, the authors propose a method for estimating the incidence of heroin use by adjusting reported numbers of heroin users visiting drug treatment agencies for the time lag between onset of heroin use and first treatment request (lag distribution). The adjusted incidence is relative, since it represents the number of individuals beginning heroin use in each year whose...

The Severity of Pandemic H1N1 Influenza in the United States, from April to July 2009: A Bayesian Analysis

Bayesian Analysis Anne M. Presanis Daniela De Angelis The New York City Swine Flu Investigation Team Angela Hagy Carrie Reed Steven Riley Ben S. Cooper Lyn Finelli Paul Biedrzycki Marc Lipsitch Lone

Modeling the percolation of annotation errors in a database of protein sequences

Public sequence databases contain information on the sequence, structure and function of proteins. Genome sequencing projects have led to a rapid increase in protein sequence information, but reliable, experimentally verified, information on protein function lags a long way behind. To address this deficit, functional annotation in protein databases is often inferred by sequence...