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Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent?

Hypotension during intermittent hemodialysis is common, and has been attributed to acute volume shifts, shifts in osmolarity, electrolyte imbalance, temperature changes, altered vasoregulation, and sheer hypovolemia. Although hypovolemia may intuitively seem a likely cause for hypotension in intensive care patients, its role in the pathogenesis of intradialytic hypotension may be...

Sexually antagonistic selection on genetic variation underlying both male and female same-sex sexual behavior

Background Intralocus sexual conflict, arising from selection for different alleles at the same locus in males and females, imposes a constraint on sex-specific adaptation. Intralocus sexual conflict can be alleviated by the evolution of sex-limited genetic architectures and phenotypic expression, but pleiotropic constraints may hinder this process. Here, we explored putative...

Heart�lung interactions during neurally adjusted ventilatory assist

Introduction Assist in unison to the patient�s inspiratory neural effort and feedback-controlled limitation of lung distension with neurally adjusted ventilatory assist (NAVA) may reduce the negative effects of mechanical ventilation on right ventricular function. Methods Heart�lung interaction was evaluated in 10 intubated patients with impaired cardiac function using esophageal...

Divergence and ontogenetic coupling of larval behaviour and thermal reaction norms in three closely related butterflies

Genetic trade-offs such as between generalist–specialist strategies can be masked by changes in compensatory processes involving energy allocation and acquisition which regulation depends on the state of the individual and its ecological surroundings. Failure to account for such state dependence may thus lead to misconceptions about the trade-off structure and nature of...

Hemodynamic assessment of critically ill patients using a miniaturized transesophageal echocardiography probe

Introduction Hemodynamic management in intensive care patients guided by blood pressure and flow measurements often do not sufficiently reveal common hemodynamic problems. Trans-esophageal echocardiography (TEE) allows for direct measurement of cardiac volumes and function. A new miniaturized probe for TEE (mTEE) potentially provides a rapid and simplified approach to monitor...

Mating success of resident versus non-resident males in a territorial butterfly

Martin Bergman Karl Gotthard David Berger Martin Olofsson Darrell J Kemp Christer Wiklund 0 School of Tropical Biology, James Cook University , PO Box 6811, Cairns, Queensland 4870 , Australia 1

Immunization with Cocktail of HIV-Derived Peptides in Montanide ISA-51 Is Immunogenic, but Causes Sterile Abscesses and Unacceptable Reactogenicity

Background A peptide vaccine was produced containing B and T cell epitopes from the V3 and C4 Envelope domains of 4 subtype B HIV-1 isolates (MN, RF, CanO, & Ev91). The peptide mixture was formulated as an emulsion in incomplete Freund's adjuvant (IFA). Methods Low-risk, healthy adult subjects were enrolled in a randomized, placebo-controlled dose-escalation study, and selected...

Current Problems Affecting Costs of Condemnation

CURRENT PROBLEMS AFFECTING COSTS OF CONDEMNATIONt DAVID BERGER 0 1 0 "lThe author gratefully acknowledges the devoted and highly intelligent assistance of Deputy to the- City Solicitor Lewis Kates