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Correction: Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial

M. Goldfarb OPEN ACCESS The dose of Lactobacillus reuteri DSM 17938 appears incorrectly throughout the article as 5x108 colony-forming units (cfu) per day. The correct dose of of Lactobacillus ... , randomized, factorial, controlled trial Jeffrey M. Pernica Andrew P. Steenhoff Margaret Mokomane Banno Moorad Kwana Lechiile Marek Smieja Loeto Mazhani Ji Cheng Matthew S. Kelly Mark Loeb Ketil Stordal David

Rapid enteric testing to permit targeted antimicrobial therapy, with and without Lactobacillus reuteri probiotics, for paediatric acute diarrhoeal disease in Botswana: A pilot, randomized, factorial, controlled trial

. Author Contributions Conceptualization: Jeffrey M. Pernica, Andrew P. Steenhoff, Margaret Mokomane, Marek Smieja, Mark Loeb, Ketil Stordal, David M. Goldfarb. Data curation: Banno Moorad. Formal ... analysis: Jeffrey M. Pernica, Ji Cheng. Funding acquisition: Jeffrey M. Pernica, Ketil Stordal, David M. Goldfarb. Investigation: Jeffrey M. Pernica, Andrew P. Steenhoff, Margaret Mokomane, Banno Moorad

Impact of Rotavirus Vaccination on Hospitalizations and Deaths From Childhood Gastroenteritis in Botswana

Background. A monovalent human rotavirus vaccine (RV1) was introduced in Botswana in July 2012. We assessed the impact of RV1 vaccination on childhood gastroenteritis-related hospitalizations and deaths in 2013 and 2014. Methods. We obtained data from registers of 4 hospitals in Botswana on hospitalizations and deaths from gastroenteritis, regardless of cause, among children <5...

Effectiveness of Monovalent Rotavirus Vaccine After Programmatic Implementation in Botswana: A Multisite Prospective Case-Control Study

Background. Botswana introduced monovalent G1P[8] rotavirus vaccine (RV1) in July 2012, providing one of the first opportunities to assess the effectiveness of routine RV1 vaccination in a high-burden setting in Africa. We sought to determine the effectiveness of RV1 against rotavirus diarrhea hospitalization using a case-control evaluation. Methods. Vaccine age-eligible children...

Severe late-onset multisystem cytomegalovirus infection in a premature neonate previously treated for congenital infection

Background Cytomegalovirus is the most common pathogen causing congenital infection and can result in significant neurodevelopmental adverse outcomes. For this reason, it is the standard of care in many regions to treat congenital cytomegalovirus infection involving the brain with six weeks of ganciclovir. There have been no reports in the published literature of significant...

Association of Respiratory Viruses with Outcomes of Severe Childhood Pneumonia in Botswana

Background The highest incidence of childhood acute lower respiratory tract infection (ALRI) is in low- and middle-income countries. Few studies examined whether detection of respiratory viruses predicts ALRI outcomes in these settings. Methods We conducted prospective cohort and case-control studies of children 1-23 months of age in Botswana. Cases met clinical criteria for...

Microbiology of Urinary Tract Infections in Gaborone, Botswana

Objective The microbiology and epidemiology of UTI pathogens are largely unknown in Botswana, a high prevalence HIV setting. Using laboratory data from the largest referral hospital and a private hospital, we describe the major pathogens causing UTI and their antimicrobial resistance patterns. Methods This retrospective study examined antimicrobial susceptibility data for urine...