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Search: authors:"Diana Klein"

4 papers found.
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iPSCs-based generation of vascular cells: reprogramming approaches and applications

Recent advances in the field of induced pluripotent stem cells (iPSCs) research have opened a new avenue for stem cell-based generation of vascular cells. Based on their growth and differentiation potential, human iPSCs constitute a well-characterized, generally unlimited cell source for the mass generation of lineage- and patient-specific vascular cells without any ethical...

Blood pressure and falls in community-dwelling people aged 60 years and older in the VHM&PP cohort

Background Falls are one of the major health problems in old people. Different risk factors were identified but only few epidemiological studies analysed the influence of conventionally measured blood pressure on falls. The objective of our study was to investigate the relationship between systolic and diastolic blood pressure and falls. Methods In 3,544 community-dwelling...

Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development

Axis Regulates Early Heart Valve Development Yidong Wang Bingruo Wu Alyssa A. Chamberlain Wendy Lui Pratistha Koirala Katalin Susztak Diana Klein Verdon Taylor Bin Zhou Masaru Katoh, National Cancer

Vascular Wall-Resident CD44+ Multipotent Stem Cells Give Rise to Pericytes and Smooth Muscle Cells and Contribute to New Vessel Maturation

Here, we identify CD44(+)CD90(+)CD73(+)CD34(−)CD45(−) cells within the adult human arterial adventitia with properties of multipotency which were named vascular wall-resident multipotent stem cells (VW-MPSCs). VW-MPSCs exhibit typical mesenchymal stem cell characteristics including cell surface markers in immunostaining and flow cytometric analyses, and differentiation into...