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Acupuncture for comorbid mild-moderate depression and chronic musculoskeletal pain: study protocol for a randomized controlled trial

Depression and chronic musculoskeletal pain (CMSP) are the leading causes of years lived with disabling diseases worldwide. Moreover, they often commonly coexist, which makes diagnosis and treatment difficult. A safe and effective treatment is urgently needed. Previous studies have shown that acupuncture is a cost-effective treatment for simple depression or CMSP. However, there...

Can passenger flow distribution be estimated solely based on network properties in public transport systems?

We present a pioneering investigation into the relation between passenger flow distribution and network properties in public transport systems. The methodology is designed in a reverse engineering fashion by utilizing passively measured passenger flow dynamics over the entire network. We quantify the properties of public transport networks using a range of centrality indicators...

miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling

Hepatocellular carcinoma (HCC) remains one of the most lethal cancers. MicroRNA-155 (miR-155) and collagen triple helix repeat containing 1 (CTHRC1) were found to be involved in hepatocarcinogenesis, but their detailed functions in HCC are unclear. Here, we aimed to investigate the underlying role of miR-155-5p and CTHRC1 in HCC. miR-155-5p and CTHRC1 expression levels were...

The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion

Aminopeptidase N (CD13) is a widely expressed cell surface metallopeptidase involved in the migration of cancer and endothelial cells. Apart from our demonstration that CD13 modulates the efficacy of tumor necrosis factor-α-induced apoptosis in neutrophils, no other function for CD13 has been ascribed in this cell. We hypothesized that CD13 may be involved in neutrophil migration...

The Roles of Integrins in Function of Human Neutrophils after Their Migration through Endothelium into Interstitial Matrix

We investigated the changes in neutrophil phenotype and function after transendothelial migration, and the roles played by integrin receptors in their behaviour. Neutrophils were tracked microscopically as they migrated through endothelial cells into collagen gels, and were retrieved at desired times. When endothelial cells were treated with increasing doses of tumour necrosis...

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and Xiaonong Fan equally contributed to this work as joint first authors

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and Xiaonong Fan equally contributed to this work as joint first authors

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and Xiaonong Fan equally contributed to this work as joint first authors

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and Xiaonong Fan equally contributed to this work as joint first authors

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... potential therapeutic strategy for ischemia stroke. Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and

A Study on the Effect of Neurogenesis and Regulation of GSK3β/PP2A Expression in Acupuncture Treatment of Neural Functional Damage Caused by Focal Ischemia in MCAO Rats

Traditional Chinese Medicine, Tianjin 300193, China Received 27 March 2014; Revised 25 May 2014; Accepted 9 June 2014; Published 10 July 2014 Academic Editor: Yi-Hung Chen Copyright © 2014 Ding Luo et al ... authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Ding Luo and Xiaonong Fan equally contributed to this work as joint first authors