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Search: authors:"Dipender Gill"

3 papers found.
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Clinical Trials of Immunomodulation in Ischemic Stroke

Inflammatory mechanisms are currently considered as a prime target for stroke therapy. There is evidence from animal studies that immune signals and mediators can have both detrimental and beneficial effects in particular stages of the disease process. Moreover, several of these mechanisms are turned on with sufficient delay after ischemia onset to make them amenable to therapeutic ...

Age at menarche and lung function: a Mendelian randomization study

A trend towards earlier menarche in women has been associated with childhood factors (e.g. obesity) and hypothesised environmental exposures (e.g. endocrine disruptors present in household products). Observational evidence has shown detrimental effects of early menarche on various health outcomes including adult lung function, but these might represent spurious associations due to ...

Progeria syndrome in CKD/ESRD

Introduction and Aims: Despite a progressively higher incidence of stroke in patients with chronic kidney disease [CKD] there is very little data on the presentation and access to acute stroke services in these populations as well as their clinical outcome. We therefore examined the association between renal function and clinical outcome measures within the UK Stroke Improvement ...