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Effect of battery longevity on costs and health outcomes associated with cardiac implantable electronic devices: a Markov model-based Monte Carlo simulation

IntroductionThe effects of device and patient characteristics on health and economic outcomes in patients with cardiac implantable electronic devices (CIEDs) are unclear. Modeling can estimate costs and outcomes for patients with CIEDs under a variety of scenarios, varying battery longevity, comorbidities, and care settings. The objective of this analysis was to compare changes...

An updated estimate of costs of endophthalmitis following cataract surgery among Medicare patients: 2010–2014

An updated estimate of costs of endophthalmitis following cataract surgery among Medicare patients: 2010–2014 Jordana K Schmier,1 Carolyn K Hulme-Lowe,1 David W Covert,2 Edmund C Lau3 1Exponent, Inc., Health Sciences, Alexandria, VA, 2Alcon Research Ltd., Fort Worth, TX, 3Exponent, Inc., Health Sciences, Menlo Park, CA, USA Background: Endophthalmitis, which can occur after...

Cancer mortality and quantitative oil production in the Amazon region of Ecuador, 1990–2010

Purpose Controversy persists over whether cancer risk is increased in communities surrounding oil fields, especially in the Oriente region of Ecuador. This ecologic study uses quantitative exposure data, updated mortality data, and improved statistical methods to study the impact of oil exploration and production activities on cancer mortality rates in the Oriente. Methods Cancer...

Two-year treatment patterns and costs in glaucoma patients initiating treatment with prostaglandin analogs

Two-year treatment patterns and costs in glaucoma patients initiating treatment with prostaglandin analogs Jordana K Schmier1, Edmund C Lau2, David W Covert31Exponent, Alexandria, VI, USA; 2Exponent, Menlo Park, CA, USA; 3Alcon Research Ltd, Fort Worth, TX, USAObjective: To determine treatment patterns and costs over a two-year period among new initiators of topical prostaglandin...

Use of electronic medical records (EMR) for oncology outcomes research: assessing the comparability of EMR information to patient registry and health claims data

Use of electronic medical records (EMR) for oncology outcomes research: assessing the comparability of EMR information to patient registry and health claims data Edmund C Lau1, Fionna S Mowat1, Michael A Kelsh1,*, Jason C Legg2, Nicole M Engel-Nitz3, Heather N Watson1, Helen L Collins2, Robert J Nordyke4,5, Joanna L Whyte21Exponent, Menlo Park, CA, USA; 2Amgen, Thousand Oaks, CA...