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Health-Related Quality of Life Subdomains in Patients with Parkinson’s Disease: The Role of Gender

Correspondence should be addressed to Elke Kalbe; ed.nleok-ku@eblaK.eklE Received 11 April 2018; Revised 12 June 2018; Accepted 4 July 2018; Published 1 August 2018 Academic Editor: Seyed-Mohammad Fereshtehnejad ... Timmermann nor any member of his family holds stocks, stock options, patents, or financial interests in any of the abovementioned companies or their competitors. Elke Kalbe reports grants from the

Decision-Making Impairments in Patients with Parkinson’s Disease

A high percentage of Parkinson’s disease (PD) patients show cognitive impairments in addition to the cardinal motor symptoms. These deficits primarily concern executive functions most probably linked to dysfunctions in prefrontal regions due to decreased dopaminergic transmission in fronto-striatal loops. To investigate possible associations between decision-making and executive...

Screening for Cognitive Impairment in Parkinson's Disease: Improving the Diagnostic Utility of the MoCA through Subtest Weighting

Background Given the high prevalence of cognitive impairment in Parkinson’s disease (PD), cognitive screening is important in clinical practice. The Montreal Cognitive Assessment (MoCA) is a frequently used screening test in PD to detect mild cognitive impairment (PD-MCI) and Parkinson’s disease dementia (PD-D). However, the proportion in which the subtests are represented in the...

Effects of cognitive training with additional physical activity compared to pure cognitive training in healthy older adults

Effects of cognitive training with additional physical activity compared to pure cognitive training in healthy older adults Julia Rahe,1 Annette Petrelli,1 Stephanie Kaesberg,2 Gereon R Fink,3 Josef Kessler,3 Elke Kalbe1 1Psychological Gerontology and Center for Neuropsychological Diagnostics and Interventions, Institute of Gerontology, University of Vechta, Vechta, Germany...

A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease

Purpose Amyloid PET tracers have been developed for in vivo detection of brain fibrillar amyloid deposition in Alzheimer’s disease (AD). To serve as an early biomarker in AD the amyloid PET tracers need to be analysed in multicentre clinical studies. Methods In this study 238 [11C]Pittsburgh compound-B (PIB) datasets from five different European centres were pooled. Of these 238...