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25 papers found.
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Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database

Conceptualization: Snigdha Jain, Rohan Khera. Data curation: Snigdha Jain. Formal analysis: Snigdha Jain, Rohan Khera. Investigation: Eric M. Mortensen, Jonathan C. Weissler. Methodology: Rohan Khera, Eric M ... . Mortensen. Supervision: Snigdha Jain, Eric M. Mortensen, Jonathan C. Weissler. Validation: Snigdha Jain, Rohan Khera, Eric M. Mortensen, Jonathan C. Weissler. Writing ± original draft: Snigdha Jain. Writing

National epidemiology of initial and recurrent Clostridium difficile infection in the Veterans Health Administration from 2003 to 2014

Conceptualization: Kelly R. Reveles, Kenneth A. Lawson, Eric M. Mortensen, Mary Jo V. Pugh, Jim M. Koeller, Christopher R. Frei. Data curation: Kelly R. Reveles, Christopher R. Frei. Formal analysis: Kelly R ... . Reveles, Christopher R. Frei. Funding acquisition: Kelly R. Reveles. Methodology: Kelly R. Reveles, Kenneth A. Lawson, Eric M. Mortensen, Mary Jo V. Pugh, Jim M. Koeller, Jacqueline R. Argamany

Not Just Pathophysiology….

to all of our patients. Corresponding Author: Eric M. Mortensen, MD, MSc, FACP; General Internal Medicine (111E), Dallas VA Medical Center, 4 5 0 0 S o u t h L a n c a s t e r, D a l l a s , Te x a s 7

Comparative-effectiveness of vancomycin and linezolid as part of guideline-recommended empiric therapy for healthcare-associated pneumonia

. Mortensen 1 6 Russell T. Attridge 5 Christopher R. Frei 0 3 4 0 Pharmacotherapy Education and Research Center (PERC), School of Medicine, University of Texas Health Science Center at San Antonio , 7703 Floyd

New Ways to Look at Old Patterns? Sequence Analysis to Analyze Patterns of Clinical Stability in Community-Acquired Pneumonia

Marisha Burden 1 Eric M. Mortensen MSc 0 0 VA North Texas Health Care System and University of Texas Southwestern Medical Center , Dallas, TX, USA 1 Denver Health, Denver Colorado and University of

Statins and New-Onset Diabetes Mellitus and Diabetic Complications: A Retrospective Cohort Study of US Healthy Adults

Background Statin use is associated with increased incidence of diabetes and possibly with increased body weight and reduced exercise capacity. Data on the long-term effects of these associations in healthy adults, however, are very limited. In addition, the relationship between these effects and diabetic complications has not been adequately studied. Objective To examine the...

Non-invasive mechanical ventilation and mortality in elderly immunocompromised patients hospitalized with pneumonia: a retrospective cohort study

Background Mortality after pneumonia in immunocompromised patients is higher than for immunocompetent patients. The use of non-invasive mechanical ventilation for patients with severe pneumonia may provide beneficial outcomes while circumventing potential complications associated with invasive mechanical ventilation. The aim of our study was to determine if the use of non...

Association of skeletal muscle relaxers and antihistamines on mortality, hospitalizations, and emergency department visits in elderly patients: a nationwide retrospective cohort study

Background High-risk medication exposure in the elderly is common and associated with increased mortality, hospitalizations, and emergency department (ED) visits. Skeletal muscle relaxants and antihistamines are high-risk medications commonly prescribed in elderly patients. The objective of this study was to determine the association between skeletal muscle relaxants or...

The Association of Cardioprotective Medications with Pneumonia-Related Outcomes

Introduction Little research has examined whether cardiovascular medications, other than statins, are associated with improved outcomes after pneumonia. Our aim was to examine the association between the use of beta-blockers, statins, angiotensin converting enzyme (ACE) inhibitors, and angiotensin II receptor blockers (ARBs) with pneumonia-related outcomes. Materials and Methods...

Comparative Value of Four Measures of Retention in Expert Care in Predicting Clinical Outcomes and Health Care Utilization in HIV Patients

This study compared the ability of four measures of patient retention in HIV expert care to predict clinical outcomes. This retrospective study examined Veterans Health Administration (VHA) beneficiaries with HIV (ICD-9-CM codes 042 or V08) receiving expert care (defined as HIV-1 RNA viral load and CD4 cell count tests occurring within one week of each other) at VHA facilities...

Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function

Hospitalization of the elderly for invasive pneumococcal disease is frequently accompanied by the occurrence of an adverse cardiac event; these are primarily new or worsened heart failure and cardiac arrhythmia. Herein, we describe previously unrecognized microscopic lesions (microlesions) formed within the myocardium of mice, rhesus macaques, and humans during bacteremic...

Racial variations in processes of care for patients with community-acquired pneumonia

Background Patients hospitalized with community acquired pneumonia (CAP) have a substantial risk of death, but there is evidence that adherence to certain processes of care, including antibiotic administration within 8 hours, can decrease this risk. Although national mortality data shows blacks have a substantially increased odds of death due to pneumonia as compared to whites...

Population-Based Study of Statins, Angiotensin II Receptor Blockers, and Angiotensin-Converting Enzyme Inhibitors on Pneumonia-Related Outcomes

Background. Studies suggest that statins and angiotensin-converting enzyme (ACE) inhibitors might be beneficial for the treatment of infections. Our purpose was to examine the association of statin, ACE inhibitor, and angiotensin II receptor blocker (ARB) use with pneumonia-related outcomes. Methods. We conducted a retrospective cohort study using Department of Veterans Affairs...

Impact of prior outpatient antibiotic use on mortality for community acquired pneumonia: a retrospective cohort study

Background The purpose of this study was to examine whether prior outpatient antibiotic use is associated with increased 30-day mortality, after adjusting for potential confounders, for those subsequently hospitalized with pneumonia. Methods A retrospective cohort study conducted at two tertiary teaching hospitals. Eligible subjects were admitted with a diagnosis of, and had a...

The impact of empiric antimicrobial therapy with a β-lactam and fluoroquinolone on mortality for patients hospitalized with severe pneumonia

Introduction National clinical practice guidelines have recommended specific empiric antimicrobial regimes for patients with severe community-acquired pneumonia. However, evidence confirming improved mortality with many of these regimes is lacking. Our aim was to determine the association between the empiric use of a β-lactam with fluoroquinolone, compared with other recommended...

The impact of prior outpatient ACE inhibitor use on 30-day mortality for patients hospitalized with community-acquired pneumonia

Background Recent studies suggest that angiotensin-converting enzyme (ACE) inhibitors may have beneficial effects for patients at risk for some types of infections. We examined the effect of prior outpatient use of ACE inhibitors on mortality for patients hospitalized with community-acquired pneumonia. Methods A retrospective cohort study conducted at two tertiary teaching...

The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia

Background Recent studies suggest that HMG-CoA reductase inhibitors ("statins") may have beneficial effects for patients at risk for some types of infections. We examined the effect of prior outpatient use of statins on mortality for patients hospitalized with community-acquired pneumonia. Methods A retrospective cohort study conducted at two tertiary teaching hospitals. Eligible...

Causes and Risk Factors for Rehospitalization of Patients Hospitalized with Community-Acquired Pneumonia

Background. Rehospitalization after inpatient treatment of community-acquired pneumonia occurs in one-tenth of all hospitalizations, but the clinical circumstances surrounding readmission to the hospital have not been well studied. The objective of this study was to identify the causes and risk factors for rehospitalization of inpatients with community-acquired pneumonia. Methods...