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Exposure to air pollution near a steel plant is associated with reduced heart rate variability: a randomised crossover study

Background Epidemiological studies have shown that as ambient air pollution (AP) increases the risk of cardiovascular mortality also increases. The mechanisms of this effect may be linked to alterations in autonomic nervous system function. We wished to examine the effects of industrial AP on heart rate variability (HRV), a measure of subtle changes in heart rate and rhythm ...

Contrasting biological potency of particulate matter collected at sites impacted by distinct industrial sources

Background Industrial sources contribute a significant proportion of anthropogenic particulate matter (PM) emissions, producing particles of varying composition that may differentially impact health. This study investigated the in vitro toxicity of ambient PM collected near industrial sites in relation to particle size and composition. Methods Size-fractionated particles ...

Cytotoxic and inflammatory potential of size-fractionated particulate matter collected repeatedly within a small urban area

Background Exposure to coarse, fine, and ultrafine particles is associated with adverse population health impacts. We investigated whether size-fractionated particles collected repeatedly in the vicinity of industrial (steel mills and associated coking operations, wastewater treatment), high traffic, and residential areas display systematic differences in biological potency. ...

Differential Regulation of the Lung Endothelin System by Urban Particulate Matter and Ozone

epidemiology tools are available to investigate such outcomes. ACKNOWLEDGMENTS Errol Thomson is the recipient of a scholarship from the Natural Sciences and Engineering Research Council of Canada and a