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39 papers found.
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Health behavior associated with liver enzymes among obese Korean adolescents, 2009–2014

Cooperation & Education Program (#NCCRI NCCI 52210± 52211, 2017) of National Cancer Center, Korea. Author Contributions Conceptualization: Eun-young Lee, Moran Ki. Formal analysis: Eun-young Lee, Moran Ki ... . Investigation: Eun-young Lee. Methodology: Hwa Young Choi, Hyunsoon Cho, Bo Hyun Kim. Project administration: Moran Ki. Software: Hwa Young Choi. Supervision: Hyunsoon Cho, Bo Hyun Kim, Moran Ki. Validation

Schwannoma of the tongue: a case report with review of literature

Background Schwannomas (or neurilemmomas) of the tongue are benign, usually solitary, encapsulated masses derived from Schwann cells. Clinical evidence indicates that schwannoma is painless and slow growing. In general, schwannoma is treated by surgical excision. Here, we describe a case of schwannoma of the tongue, include a review of the literature from 1955 to 2016, and provide ...

Pubertal development and screen time among South Korean adolescents: testing body mass index and psychological well-being as mediators

Background This study tested links between pubertal development and screen time among South Korean adolescent boys and girls. Methods Secondary analysis was conducted on data from the Korean Children and Youth Panel Study (KCYPS) involving 2071 adolescents (age M = 13.14 years). Body mass index (BMI) at Grade 8 (baseline), self-esteem and depression at Grade 9 were examined as ...

Pubertal development and screen time among South Korean adolescents: testing body mass index and psychological well-being as mediators

Background This study tested links between pubertal development and screen time among South Korean adolescent boys and girls. Methods Secondary analysis was conducted on data from the Korean Children and Youth Panel Study (KCYPS) involving 2071 adolescents (age M = 13.14 years). Body mass index (BMI) at Grade 8 (baseline), self-esteem and depression at Grade 9 were examined as ...

Intra-dialytic hypertension is associated with high mortality in hemodialysis patients

Contributions Conceptualization: Eun Young Lee. Formal analysis: Jae Seok Park. Writing ± original draft: Chi-Young Choi. Data curation: Jae Seok Park, Kyu Tae Yoon, Hyo Wook Gil, Eun Young Lee, Sae Yong Hong

Body weight misperception and psychological distress among young South Korean adults: the role of physical activity

Background Emerging evidence suggests that body weight misperception may be associated with psychological distress among people in developed countries. Participating in physical activity (PA) may negate the association between weight misperception and psychological distress given the well-known benefits of PA on psychological health. This study examined the role of PA in ...

Polyphase tectonic subsidence evolution of the Vienna Basin inferred from quantitative subsidence analysis of the northern and central parts

Geodynamics and Sedimentology, University of Vienna , Althanstrasse 14, 1090 Vienna , Austria 1 Eun Young Lee The Vienna Basin is a tectonically complex Neogene basin situated at the Alpine-Carpathian

Contingent association between the size of the social support network and osteoporosis among Korean elderly women

Conceptualization: Yoosik Youm, Yumie Rhee. Data curation: Seungwon Lee, Da Hea Seo, Kyoung Min Kim, Eun Young Lee, Hyeon Chang Kim, Chang Oh Kim, Yoosik Youm, Yumie Rhee. Formal analysis: Seungwon Lee, Yoosik ... Youm. Funding acquisition: Chang Oh Kim. Investigation: Da Hea Seo, Kyoung Min Kim, Eun Young Lee, Hyeon Chang Kim, Chang Oh Kim, Yoosik Youm. Methodology: Seungwon Lee, Yoosik Youm, Yumie Rhee

Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice

The aim of this study was to evaluate the effects of sarpogrelate hydrochloride (SH), a selective serotonin 2A receptor antagonist, on diabetic nephropathy in a type 2 diabetes mouse model. We treated db/m and db/db mice with SH (30 mg/kg/day) for 12 weeks. Rat renal proximal tubule cells (NRK-52E) and mouse macrophages (Raw 264.7) were stimulated by high glucose (30 mM glucose) or ...

Patients with Rheumatoid Arthritis Show Altered Lipoprotein Profiles with Dysfunctional High-Density Lipoproteins that Can Exacerbate Inflammatory and Atherogenic Process

Objective In order to identify putative biomarkers in lipoprotein, we compared lipid and lipoprotein properties between rheumatoid arthritis (RA) patients and control with similar age. Methods We analyzed four classes of lipoproteins (VLDL, LDL, HDL2, HDL3) from both male (n = 8, 69±4 year-old) and female (n = 25, 53±7 year-old) rheumatoid arthritis (RA) patients as well as ...

Impact of Dose Tapering of Tumor Necrosis Factor Inhibitor on Radiographic Progression in Ankylosing Spondylitis

Objective To investigate the impact of dose reduction of tumor necrosis factor inhibitor (TNFi) on radiographic progression in ankylosing spondylitis (AS). Methods One hundred and sixty-five patients treated with etanercept or adalimumab were selected from a consecutive single-center observational cohort based on the availability of radiographs at baseline and after two- and/or ...

Efficacy, Safety and Pharmacokinetics of Up to Two Courses of the Rituximab Biosimilar CT-P10 Versus Innovator Rituximab in Patients with Rheumatoid Arthritis: Results up to Week 72 of a Phase I Randomized Controlled Trial

Background CT-P10 is a biosimilar of innovator rituximab (RTX), a biological therapy used to treat patients with rheumatoid arthritis (RA) who have responded inadequately to anti-tumor necrosis factor agents. Objective Our objective was to compare the clinical profile of CT-P10 versus RTX in patients with RA who received up to two courses of treatment and were followed for up to 72 ...

Efficacy and Safety of Switching from Innovator Rituximab to Biosimilar CT-P10 Compared with Continued Treatment with CT-P10: Results of a 56-Week Open-Label Study in Patients with Rheumatoid Arthritis

Background CT-P10 is a biosimilar candidate of innovator rituximab (RTX) that demonstrated a comparable clinical profile to RTX in a phase I randomized controlled trial (RCT) in rheumatoid arthritis (RA) (ClinicalTrials.gov identifier: NCT01534884). Objective This open-label extension (OLE) study (NCT01873443) compared the efficacy and safety of CT-P10 in patients with RA who ...

Space maintenance in autogenous fresh demineralized tooth blocks with platelet-rich plasma for maxillary sinus bone formation: a prospective study

This prospective study evaluated the effectiveness of autogenous fresh demineralized tooth block (Auto-FDT block) with platelet-rich plasma (PRP) for maxillary sinus augmentation with simultaneous implant installation. Auto-FDT block with PRP was used in Group 1 (n = 15) and combined graft (allograft and xenograft) powder with PRP was used in Group 2 (n = 15). For up to 2 years ...

Various autogenous fresh demineralized tooth forms for alveolar socket preservation in anterior tooth extraction sites: a series of 4 cases

The aim of this study was to evaluate the clinical relevance of autogenous fresh demineralized tooth (Auto-FDT) prepared at chairside immediately after extraction for socket preservation. Teeth were processed to graft materials in block, chip, or powder types immediately after extraction. Extraction sockets were filled with these materials and dental implants were installed ...

Mice Deficient in Interferon-Gamma or Interferon-Gamma Receptor 1 Have Distinct Inflammatory Responses to Acute Viral Encephalomyelitis

Interferon (IFN)-gamma is an important component of the immune response to viral infections that can have a role both in controlling virus replication and inducing inflammatory damage. To determine the role of IFN-gamma in fatal alphavirus encephalitis, we have compared the responses of wild type C57BL/6 (WTB6) mice with mice deficient in either IFN-gamma (GKO) or the alpha-chain ...

C-C Chemokine Receptor 2 Inhibitor Ameliorates Hepatic Steatosis by Improving ER Stress and Inflammation in a Type 2 Diabetic Mouse Model

Hepatic steatosis is the accumulation of excess fat in the liver. Recently, hepatic steatosis has become more important because it occurs in the patients with obesity, type 2 diabetes, and hyperlipidemia and is associated with endoplasmic reticulum (ER) stress and insulin resistance. C-C chemokine receptor 2 (CCR2) inhibitor has been reported to improve inflammation and glucose ...

Safety of Resuming Tumor Necrosis Factor Inhibitors in Ankylosing Spondylitis Patients Concomitant with the Treatment of Active Tuberculosis: A Retrospective Nationwide Registry of the Korean Society of Spondyloarthritis Research

Internal Medicine, Kyung Hee University Medical center, Seoul, Korea; Eun Young Lee, Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea; Jaejoon Lee