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Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications

The authors would like to thank the technicians, Nina Sejthen, Christina Grønhøj and Dorte Skriver-Jensen for their excellent work. Author Contributions Conceptualization: Eva Gravesen, Anders ... Nordholm, Maria Mace, Carsten Nielsen, Andreas Kjñr, Klaus Olgaard, Ewa Lewin. Data curation: Eva Gravesen, Anders Nordholm, Marya Morevati, Carsten Nielsen, Klaus Olgaard, Ewa Lewin. Formal analysis

Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia

of Nephrology, The Sophus Jacobsen and his wife Astrid Jacobsen’s Foundation, and The Kirsten and Freddy Johansen Foundation. Compliance with Ethical Standards Conflict of interest Maria L Mace, Eva ... Gravesen, Anders Nordholm, Klaus Olgaard, and Ewa Lewin declare they have no competing interests. Human and Animal Rights and Informed Consent All animal experiments were carried out in accordance with the

Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

Foundation (grant no: R1262012-12320), University of Copenhagen, The Danish Kidney Association and The Danish Nephrological Society. Author Contributions Conceptualization: Eva Gravesen, Maria Lerche Mace ... , Anders Nordholm, Jacob Hofman Bang, Keith Hruska, Carsten Haagen Nielsen, Andreas Kjñr, Klaus Olgaard, Ewa Lewin. Formal analysis: Eva Gravesen, Maria Lerche Mace, Anders Nordholm, Jacob Hofman-Bang

A potential kidney - bone axis involved in the rapid minute-to-minute regulation of plasma Ca2+

Nordholm et al. BMC Nephrology A potential kidney - bone axis involved in the 2+ rapid minute-to-minute regulation of plasma Ca Anders Nordholm 1 Maria L Mace 1 Eva Gravesen 0 Klaus Olgaard 0 Ewa

High dose intravenous iron, mineral homeostasis and intact FGF23 in normal and uremic rats

Background High iron load might have a number of toxic effects in the organism. Recently intravenous (iv) iron has been proposed to induce elevation of fibroblast growth factor 23 (FGF23), hypophosphatemia and osteomalacia in iron deficient subjects. High levels of FGF23 are associated with increased mortality in the chronic kidney disease (CKD) population. CKD patients are often...