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A comparative study of chondroitin sulfate and heparan sulfate for directing three-dimensional chondrogenesis of mesenchymal stem cells

’ information Tianyi Wang, Ph.D. is a recently graduated Ph.D. student in Bioengineering from Stanford University. Fan Yang, Ph.D., is an Associate Professor with joint appointments in the Departments of ... Yang 0 1 0 Department of Orthopaedic Surgery, Stanford University School of Medicine , 300 Pasteur Dr., Edwards R105, Stanford, CA 94305-5341 , USA 1 Department of Bioengineering, Stanford University

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

-like repeat domain; CAP, capsaicin; cryo-EM, Cryoelectron microscopy; MD, molecular dynamics; TRPV1, transient receptor potential vanilloid 1. COMPLIANCE WITH ETHICS GUIDELINES Fan Yang and Jie Zheng

Large strain detection of SRM composite shell based on fiber Bragg grating sensor

There may be more than 2% strain of carbon fiber composite material on solid rocket motor (SRM) in some extreme cases. A surface-bonded silica fiber Bragg grating (FBG) strain sensor coated by polymer is designed to detect the large strain of composite material. The strain transfer relation of the FBG large strain sensor is deduced, and the strain transfer mechanism is verified...

Intralobar pulmonary sequestration displayed as localized emphysema on computed tomography image

Pulmonary sequestration is a relatively rare condition in which a systemic artery supplies blood to an abnormal lung tissue and the normal connection with the bronchial tree is absent. It can be displayed as various signs on the computed tomography image, but emphysema is extremely rare. We describe the case of a 35-year-old man with intralobar pulmonary sequestration that...

Reconciliation and Peace Building in International Relations: An Empirical Analysis of Five Cases

October 2015 to September 2016. His fields of interest include political economy, international relations of the Asia–Pacific region, and Chinese foreign policy. Fan Yang is a graduate student at the School

Antioxidant, antiapoptotic and amino acid balance regulating activities of 1,7-dihydroxy-3,4,8-trimethoxyxanthone against dimethylnitrosamine-induced liver fibrosis

Yang, Han-Jie Jiang, Wan Li, Yi Sun. Funding acquisition: Xiao-Ping Pu. Investigation: Xi-Yuan Zheng, Xin Zhao, Ying-Fan Yang, Han-Jie Jiang, Wan Li, Yi Sun. Methodology: Xi-Yuan Zheng, Xin Zhao ... Founder Group & Peking University Health Science Center (No. Founder 201004). Author Contributions Conceptualization: Xi-Yuan Zheng, Yi Sun, Xiao-Ping Pu. Data curation: Xi-Yuan Zheng, Xin Zhao, Ying-Fan

Media:Culture:Policy, or What we talk about when we talk about (cultural) policy

The relationship between culture and policy has long been a major topic for media and cultural studies. With this issue, we hope to broaden the meaning of cultural policy, from policies that are explicitly regulating something we call the “cultural” (including media or traditional rituals or symbols) to include the practice of policy-making and the cultural legitimation of law...

Wnt/β-catenin signaling pathway inhibits the proliferation and apoptosis of U87 glioma cells via different mechanisms

). Author Contributions Conceptualization: Liyang Gao, Bing Chen. Data curation: Liyang Gao, Jinhong Li, Fan Yang, Xuecheng Cen, Zhuangbing Liao, Xiao'ao Long. Formal analysis: Liyang Gao, Jinhong Li. 16 ... / 19 Funding acquisition: Liyang Gao, Bing Chen. Investigation: Liyang Gao, Bing Chen. Methodology: Liyang Gao, Bing Chen, Jinhong Li, Fan Yang, Xuecheng Cen, Zhuangbing Liao, Xiao'ao Long. Project

Asymptotic Robustness Study of the Polychoric Correlation Estimation

Shaobo Jin and Fan Yang-Wallentin Asymptotic robustness against misspecification of the underlying distribution for the polychoric correlation estimation is studied. The asymptotic normality of

Characterization and physical mapping of nuclear ribosomal RNA (rRNA) genes in the haploid gametophytes of Saccharina japonica (Phaeophyta)

Nuclear tandemly repeated ribosomal RNA genes (18S-5.8S-25S rDNA and 5S rDNA) have been proven to be excellent cytogenetic markers for karyotype analysis of various higher plants by using the fluorescence in situ hybridization (FISH) technique. To illustrate physical mapping of these rDNAs in brown seaweed, Saccharina japonica, chromosomes, an approximately 5400-bp transcription...

The specific host plant DNA detection suggests a potential migration of Apolygus lucorum from cotton to mungbean fields

The polyphagous mirid bug Apolygus lucorum (Heteroptera: Miridae) has more than 200 species of host plants and is an insect pest of important agricultural crops, including cotton (Gossypium hirsutum) and mungbean (Vigna radiata). Previous field trials have shown that A. lucorum adults prefer mungbean to cotton plants, indicating the considerable potential of mungbean as a trap...

Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor

New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. Current techniques limit radiosynthesis to analogs of the COX-2 inhibitors with fluorine-18 added via a carbon chain, or on an aromatic position which renders the...

Quantitative comparison of motion history image variants for video-based depression assessment

Depression is the most prevalent mood disorder and a leading cause of disability worldwide. Automated video-based analyses may afford objective measures to support clinical judgments. In the present paper, categorical depression assessment is addressed by proposing a novel variant of the Motion History Image (MHI) which considers Gabor-inhibited filtered data instead of the...

Surgical resection of pulmonary metastases from colorectal cancer: 11 years of experiences

Objective To analyze the benefits and prognostic factors after surgical resection of pulmonary metastases from colorectal cancer (CRC). Methods From Jan. 2004 to Jan. 2015, continuous 88 cases diagnosed with pulmonary metastases from CRC, including 15 cases of synchronous metastases and 73 metachronous metastases, were analyzed in the retrospective study. Results All of these 88...

“Internet+” approach to mapping exposure and seismic vulnerability of buildings in a context of rapid socioeconomic growth: a case study in Tangshan, China

This paper presents the development of an “Internet+” approach to mapping exposure and seismic vulnerability of buildings in a context of rapid socioeconomic growth. This approach is a combination of the following interdependent components: (1) extraction of footprint areas of a large number of buildings from high-resolution Google Earth images; (2) estimation of floor numbers of...

Performance of Nano-Submicron-Stripe Pd Thin-Film Temperature Sensors

Dozens of small dual-beam thin-film temperature sensors with a total width down to 430 nm were fabricated and tested. The sensors were all made from 90-nm-thick Pd thin films, where the width of the narrow stripes was 70–100 nm and that of the wide ones was 210–800 nm. Two different calibration methods showed consistent and repeatable sensitivities of 0.7–1.2 μV/K for the sensors...

An experimental study of the intrinsic stability of random forest variable importance measures

Background The stability of Variable Importance Measures (VIMs) based on random forest has recently received increased attention. Despite the extensive attention on traditional stability of data perturbations or parameter variations, few studies include influences coming from the intrinsic randomness in generating VIMs, i.e. bagging, randomization and permutation. To address...

Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii

We have used an insertional mutagenesis approach to generate new C. reinhardtii motility mutants. Of 56 mutants isolated, one is a new allele at the ODA3 locus, called oda3-6. Similar to the previously characterized oda3 alleles, oda3-6 has a slow-jerky swimming phenotype and reduced swimming speed. The oda3-6 mutant fails to assemble the outer dynein arm motor and outer dynein...

Testosterone improves the differentiation efficiency of insulin-producing cells from human induced pluripotent stem cells

Human induced pluripotent stem cells (hiPSCs) may provide potential resource for regenerative medicine research, including generation of insulin-producing cells for diabetes research and insulin production. Testosterone (T) is an androgen hormone which promotes protein synthesis and improves the management of type 2 diabetes in clinical studies. Concurrently, co-existed...