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Sustainable development of environmental protection talents training: Research on the behavior decision of government, university and enterprise under the background of evolutionary game

, Xieling Li, Fang Gao, Siyuan Qiu. Resources: Lingling Zhan, Xieling Li. Software: Jinxia Wang, Yunfeng Tan. Supervision: Jinxia Wang, Lingling Zhan. Validation: Jinxia Wang, Yunfeng Tan. Visualization ... : Jinxia Wang, Fang Gao, Siyuan Qiu. Writing – original draft: Jinxia Wang, Yunfeng Tan. Writing – review & editing: Jinxia Wang, Yunfeng Tan. References 1. Filho WL, Tripathi SK, Guerra J, Giné-Garriga R

Study protocol for a randomised controlled trial to investigate the effectiveness of thoracic epidural and paravertebral blockade in reducing chronic post-thoracotomy pain: 2 (TOPIC 2)

Thoracotomy is considered one of the most painful surgical procedures and can cause debilitating chronic post-surgical pain lasting months or years postoperatively. Aggressive management of acute pain resulting from thoracotomy may reduce the likelihood of developing chronic pain. This trial compares the two most commonly used modes of acute analgesia provision at the time of...

A qualitative study exploring the lived experiences of patients living with mild, moderate and severe frailty, following hip fracture surgery and hospitalisation

. The authors would also like to thank Teresa Melody, Anne Deverill and members of the Clinical Ambassador Research Conceptualization: Vanisha Patel, Antje Lindenmeyer, Fang Gao, Joyce Yeung. Data ... curation: Vanisha Patel, Antje Lindenmeyer, Fang Gao, Joyce Yeung. Formal analysis: Vanisha Patel, Antje Lindenmeyer, Fang Gao, Joyce Yeung. Investigation: Vanisha Patel. Methodology: Vanisha Patel, Antje

Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis

Disruption of brain barriers is considered to be involved in the pathogenesis of neuronal surface antibody-associated autoimmune encephalitis (NSAE), but few studies have focused on their relationship. We aimed to explore the association between the integrity of brain barriers and clinical and paraclinical characteristics in patients with NSAE. This retrospective study...

Genome insights from the identification of a novel Pandoraea sputorum isolate and its characteristics

. (XLSX) Author Contributions Data curation: Rui-Fang Gao, Ying Wang. Formal analysis: Rui-Fang Gao, Zhi-Wen Wang. Funding acquisition: Ying Wang, Gui-Ming Zhang. Investigation: Rui-Fang Gao. Methodology ... : Rui-Fang Gao, Zhi-Wen Wang. Project administration: Rui-Fang Gao. Resources: Rui-Fang Gao, Ying Wang. Software: Zhi-Wen Wang. Validation: Rui-Fang Gao. Writing – original draft: Rui-Fang Gao. 17

Author Correction: Randomised feasibility study of prehospital recognition and antibiotics for emergency patients with sepsis (PhRASe)

Greg Fegan Theresa Foster Nick Francis Saiful Islam Matt Morgan Prabath W. B. Nanayakkara Gavin D. Perkins Alison Porter Timothy Rainer Samuel Ricketts Bernadette Sewell Tracy Shanahan Fang Gao Smith

RvD1 accelerates the resolution of inflammation by promoting apoptosis of the recruited macrophages via the ALX/FasL-FasR/caspase-3 signaling pathway

The uncontrolled inflammatory response caused by a disorder in inflammation resolution is one of the reasons for acute respiratory distress syndrome (ARDS). The macrophage pool markedly expands when inflammatory monocytes, known as recruited macrophages, migrate from the circulation to the lung. The persistent presence of recruited macrophages leads to chronic inflammation in the...

Randomised feasibility study of prehospital recognition and antibiotics for emergency patients with sepsis (PhRASe)

Bernadette Sewell 7 9 Tracy Shanahan 1 7 Fang Gao Smith 7 10 Michael A. Smyth 6 7 Helen Snooks 0 7 Chris Moore 7 8 0 Swansea University Medical School , ILS2, Singleton Campus, Wales SA2 8PP , UK 1 Cardiff and

Validation of the Clinical Assessment Scale for Autoimmune Encephalitis: A Multicenter Study

A new scale, named the Clinical Assessment Scale for Autoimmune Encephalitis (CASE), has recently been developed for rating the severity of autoimmune encephalitis (AE) with a high level of clinimetric properties. In this study, our primary objective was to validate the performance of CASE through a multicenter study in China. Between July 2014 and December 2019, 143 consecutive...

LINC00261: a burgeoning long noncoding RNA related to cancer

Long noncoding RNAs (lncRNAs), are transcripts longer than 200 nucleotides that are considered to be vital regulators of many cellular processes, particularly in tumorigenesis and cancer progression. long intergenic non-protein coding RNA 261 (LINC00261), a recently discovered lncRNA, is abnormally expressed in a variety of human malignancies, including pancreatic cancer, gastric...

ChromInst: A single cell sequencing technique to accomplish pre-implantation comprehensive chromosomal screening overnight

applications. Supporting information S1 Raw images. The original image of Fig 2. (PDF) Author Contributions Conceptualization: Si-Jia Lu, Jun Ren. Data curation: Fang-Fang Gao, Li Chen, Shi-Ping Bo, Ya-Xin ... Yao. Formal analysis: Fang-Fang Gao, Li Chen, Shi-Ping Bo, Ya-Xin Yao. Funding acquisition: Si-Jia Lu. Investigation: Fang-Fang Gao, Li Chen. Methodology: Fang-Fang Gao, Jun Ren. Project

Glycoconjugate vaccines against Salmonella enterica serovars and Shigella species: existing and emerging methods for their analysis

HPAEC-PAD analysis, which was supervised by Fang Gao and Barbara Bolgiano. Funding Funding to A.B. was provided by the National Centre for Macromolecular Hydrodynamics, School of Biosciences, University

Risk factors associated with the severity of obstructive sleep apnea syndrome among adults

Obstructive sleep apnea syndrome (OSAS) is a complete or partial airway obstruction that causes significant physiologic disturbance with various clinical impacts. The aim of the study was to determine the risk factors associated with the severity of OSAS. 303 patients with OSAS and 199 patients without OSAS enrolled in the sleep disorder center from 2017 to 2019 were included in...

Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes

This retrospective analysis evaluated the interaction between Ki-67 and histological grade and their prognostic role in different breast cancer subtypes. In total, 2,573 breast cancer patients underwent surgery, and their histological grade and Ki-67 values were evaluated by breast pathologists. The median Ki-67 index was 15%, which was used as the cut-off for low/high Ki-67...

The Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT

In the era of intensity-modulated radiotherapy (IMRT), it is important to analyse the prognostic value of deficient mismatch repair (dMMR) in nasopharyngeal carcinoma (NPC). In this study, in pretreatment biopsies of 69 patients with stage II–IVa NPC, the expression levels of MMR proteins, including MLH1, MSH2, MSH6 and PMS2, were assessed by immunohistochemistry (IHC). The...

32A9, a novel human antibody for designing an immunotoxin and CAR-T cells against glypican-3 in hepatocellular carcinoma

of China (No. 81773260, No. 81972284) and the National Natural Science Foundation Youth Project of Jiangsu, China (No. BK20171047). Author information Author notes Xiaoyu Liu, Fang Gao and Longwei ... , People’s Republic of China Xiaoyu Liu, Fang Gao, Lei Ao, Ming Lu, Liming Gou & Wei Gao Department of Biotherapy, Nanjing Jinling Hospital, Nanjing, Jiangsu, 210002, People’s Republic of China Longwei

Selection of culture conditions for callus induction and proliferation by somatic embryogenesis of Pinus koraiensis

; Megagametophytes; Embryonic maintenance - Fang Gao and Chunxue Peng have are equal to this work. significantly affected callus induction (induction rate reached 1.67%). Embryogenic maintenance and callus

Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

Gastrin-releasing peptide (GRP) functions as a neurotransmitter for non-histaminergic itch, but its site of action (sensory neurons vs spinal cord) remains controversial. To determine the role of GRP in sensory neurons, we generated a floxed Grp mouse line. We found that conditional knockout of Grp in sensory neurons results in attenuated non-histaminergic itch, without impairing...

Risk Assessment of Sarcopenia in Patients With Type 2 Diabetes Mellitus Using Data Mining Methods

Purpose: Sarcopenia is a geriatric syndrome, and it is closely related to the prevalence of type 2 diabetes mellitus (T2DM). Until now, the diagnosis of sarcopenia requires Dual Energy X-ray Absorptiometry (DXA) scanning. This study aims to make risk assessment of sarcopenia with support vector machine (SVM) and random forest (RF) when DXA is not available.Methods: Firstly, we...

Effects of glucagon-like peptide-1 analogue liraglutide on autophagy of human umbilical vein endothelial cells in high glucose conditions

Objective  To explore the effect of glucagon-like peptide-1 (GLP-1) analogue liraglutide (LIRA) on autophagy of human umbilical vein endothelial cells (HUVECs) under high glucose condition, and its corresponding mechanism. Methods  (1) The HUVECs were cultured in vitro and assigned to control group (group A) and high glucose group (group B). Group A and B were cultured...