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The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway

The purpose of this study was to investigate the protective mechanism of HDAC2 inhibitor CAY10683 on intestinal mucosal barrier in acute liver failure (ALF). In order to establish ALF-induced intestinal epithelial barrier disruption models, D-galactosamine/LPS and LPS were, respectively, used with rats and NCM460 cell and then administrated with CAY10683. Transepithelial...

Design of a Compact Broadband 90° Waveguide Twist Based on Double-Corner-Cut Square Slots

A new compact broadband waveguide twist by double-corner-cut square slots is presented. In particular, the proposed module is made from two substrate layers and three copper cladding layers, which can be used as the waveguide twist and broadband filter. A double-corner-cut square slot is etched on each metal layer with relative rotation. It is found that the optimized module can...

Numerical Simulation and Experimental Study on the Gas-Solid Coupling of the Aerostatic Thrust Bearing with Elastic Equalizing Pressure Groove

Aiming at the problem of low stiffness of aerostatic bearing, according to the principle of gas-solid coupling, this paper designs a kind of aerostatic thrust bearing with elastic equalizing pressure groove (EEPG) and investigates the effect of elastic equalizing pressure groove (EEPG) on the stiffness of aerostatic bearing. According to the physical model of the bearing, one...

Tunable critical temperature for superconductivity in FeSe thin films by pulsed laser deposition

, Jie Yuan, Ge He, Wei Hu, Zefeng Lin, Dong Li, Xingyu Jiang, Yulong Huang, Shunli Ni, Beiyi Zhu, Xiaoli Dong, Fang Zhou, Zhongxian Zhao & Kui JinKey Laboratory of Vacuum Physics, School of Physical ... Sciences, University of Chinese Academy of Sciences, Beijing, 100049, ChinaZhongpei Feng, Jie Yuan, Ge He, Wei Hu, Zefeng Lin, Dong Li, Xingyu Jiang, Yulong Huang, Shunli Ni, Xiaoli Dong, Fang Zhou

Spatiotemporal properties of microsaccades: Model predictions and experimental tests

University, Huaibei 235000, ChinaJian-Fang Zhou, Wu-Jie Yuan & Zhao ZhouCollege of Information, Huaibei Normal University, Huaibei 235000, ChinaWu-Jie Yuan AuthorsSearch for Jian-Fang Zhou in:Nature Research

Understanding positive feedback between PNA and synoptic eddies by eddy structure decomposition method

In the upper troposphere during winter, positive synoptic eddy (SE) feedback plays an indispensible role in maintaining the Pacific–North American (PNA) pattern that dominates climate variability on inter-annual timescales over the North Pacific and downstream regions. This study shows that the eddy forcing, induced by eddy-vorticity (EV) fluxes, is not only in-phase with, but...

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

Background Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of genetic information have been implicated in many diseases and are known to participate in many physiological processes. Here, we investigate the therapeutic potential of exosomes from human embryonic stem cell...

Comparative transcriptome profiling of the fertile and sterile flower buds of a dominant genic male sterile line in sesame (Sesamum indicum L.)

Background Sesame (Sesamum indicum L.) is a globally important oilseed crop with highly-valued oil. Strong hybrid vigor is frequently observed within this crop, which can be exploited by the means of genic male sterility (GMS). We have previously developed a dominant GMS (DGMS) line W1098A that has great potential for the breeding of F 1 hybrids. Although it has been genetically...

An integrated factor analysis model for product eco-design based on full life cycle assessment

Purpose: Among the methods of comprehensive analysis for a product or an enterprise, there exist defects and deficiencies in traditional standard cost analyses and life cycle assessment methods. For example, some methods only emphasize one dimension (such as economic or environmental factors) while neglecting other relevant dimensions. This paper builds a factor analysis model of...

Model predictions of features in microsaccade-related neural responses in a feedforward network with short-term synaptic depression

, ChinaJian-Fang Zhou, Wu-Jie Yuan & Zhao ZhouDepartment of Physics, Centre for Nonlinear Studies and the Beijing-Hong Kong-Singapore Joint Centre for Nonlinear and Complex Systems (Hong Kong), Institute of ... Centre, HKBU Institute of Research and Continuing Education, Virtual University Park Building, South Area Hi-tech Industrial Park, Shenzhen, ChinaChangsong Zhou AuthorsSearch for Jian-Fang Zhou in:Nature

Assessment of potential factors associating with costs of hospitalizing cardiovascular diseases in 141 hospitals in Guangxi, China

Background The rising cost of healthcare is of great concern in China, as evidenced by the media features negative reports almost daily. However there are only a few studies from well-developed cities, like Beijing or Shanghai, and little is known about healthcare costs in rest of the country. In this study, we use hospitalization summary reports (HSRs) from admitted...

Heralded quantum repeater based on the scattering of photons off single emitters using parametric down-conversion source

, Beijing Normal University, Beijing 100875, ChinaGuo-Zhu Song, Fang-Zhou Wu, Mei Zhang & Guo-Jian Yang AuthorsSearch for Guo-Zhu Song in:Nature Research journals • PubMed • Google ScholarSearch for Fang-Zhou

CA153 in Breast Secretions as a Potential Molecular Marker for Diagnosing Breast Cancer: A Meta Analysis

Purpose Many studies have reported that carbohydrate antigen 153 (CA153) in breast secretions (BS) can discriminate breast cancer (BC) patients from healthy individuals, indicating CA153 in BS as a potential index for BC. This meta-analysis aimed to evaluate the actual diagnostic value of CA153 in BS. Methods Related papers were obtained from Pubmed, Embase, Scopus, Ovid...

Convergence rate of solutions toward stationary solutions to the bipolar Navier-Stokes-Poisson equations in a half line

In this paper, we show the convergence rate of a solution toward the stationary solution to the initial boundary value problem for the one-dimensional bipolar compressible Navier-Stokes-Poisson equations. For the supersonic flow at spatial infinity, if an initial perturbation decays with the algebraic or the exponential rate in the spatial asymptotic point, the solution converges...

A VidEo-Based Intelligent Recognition and Decision System for the Phacoemulsification Cataract Surgery

The phacoemulsification surgery is one of the most advanced surgeries to treat cataract. However, the conventional surgeries are always with low automatic level of operation and over reliance on the ability of surgeons. Alternatively, one imaginative scene is to use video processing and pattern recognition technologies to automatically detect the cataract grade and intelligently...

The Use of Weighted Graphs for Large-Scale Genome Analysis

There is an acute need for better tools to extract knowledge from the growing flood of sequence data. For example, thousands of complete genomes have been sequenced, and their metabolic networks inferred. Such data should enable a better understanding of evolution. However, most existing network analysis methods are based on pair-wise comparisons, and these do not scale to...

ISART: A Generic Framework for Searching Books with Social Information

Effective book search has been discussed for decades and is still future-proof in areas as diverse as computer science, informatics, e-commerce and even culture and arts. A variety of social information contents (e.g, ratings, tags and reviews) emerge with the huge number of books on the Web, but how they are utilized for searching and finding books is seldom investigated. Here...

An Efficient Signal Reconstruction Algorithm for Stepped Frequency MIMO-SAR in the Spotlight and Sliding Spotlight Modes

Multiple-input multiple-output (MIMO) synthetic aperture radar (SAR) using stepped frequency (SF) waveforms enables a high two-dimensional (2D) resolution with wider imaging swath at relatively low cost. However, only the stripmap mode has been discussed for SF MIMO-SAR. This paper presents an efficient algorithm to reconstruct the signal of SF MIMO-SAR in the spotlight and...

Myocyte-specific enhancer factor 2C: a novel target gene of miR-214-3p in suppressing angiotensin II-induced cardiomyocyte hypertrophy

number: 2014A030313635. Author information Author notesChun-Mei Tang & Fang-zhou Liu These authors contributed equally to this work. AffiliationsGuangdong Cardiovascular Institute, Guangdong Provincial ... Key Laboratory of Clinical Pharmacology, Guangzhou 510080, ChinaChun-Mei Tang, Fang-zhou Liu, Jie-Ning Zhu, Yong-Heng Fu, Qiu-Xiong Lin, Chun-Yu Deng, Zhi-Qin Hu, Hui Yang, Shu-Lin Wu & Zhi-Xin