for Fangfang Zhao in:PubMed • Google Scholar Search for Min Zhang in:PubMed • Google Scholar Contributions MZ designed the study and edited the final version of the manuscript; PC and NY conducted
to jurisdictional claims in published maps and institutional affiliations. Author information Author notes Chunbao Zang and Fangfang Zhao contributed equally to this work AffiliationsDepartment of ... Anhui Medical University, Hefei, 230031, Anhui, ChinaLei Hua AuthorsSearch for Chunbao Zang in:PubMed • Google Scholar Search for Fangfang Zhao in:PubMed • Google Scholar Search for Lei Hua in:PubMed
, Huitong Zhou, Yuzhu Luo, and Jon G. H. Hickford conceived and designed the project. Shaobin Li, Hua Gong, and Fangfang Zhao performed the experiments. Huitong Zhou, Shaobin Li, and Jiqing Wang analyzed the
As one of the hallmarks of cancer, chemoresistance hinders curative cancer chemotherapy in osteosarcoma (OS). MicroRNAs (miRNAs) act as key regulators of gene expression in diverse biological processes including the multi-chemoresistance of cancers. Based on the CCK8 experiments, we performed an RNA-seq-based miR-omic analysis of osteosarcoma (OS) cells (a multi-chemosensitive OS...
Keratin-associated proteins (KAPs) are structural components of wool and hair fibres, and are believed to play a role in defining the physico-mechanical properties of the wool fibre. In this study, the putative ovine homologue of the human KAP26-1 gene (KRTAP26-1) was sequenced and four variants (named A–D) were identified. The sequences shared some identity with each other and...
MiR-34a-5p has been implicated in the tumorigenesis and progression of several types of cancer. However, the role of miR-34a-5p in osteosarcoma (OS) remains largely unknown. This study was performed in two multi-chemosensitive (G-292 and MG63.2) and two resistant (SJSA-1 and MNNG/HOS) OS cell lines. MiR-34a-5p promotes OS multi-chemoresistance via its repression of the Delta-like...
Background Chemoresistance hinders the curative cancer chemotherapy. MicroRNAs (miRNAs) are key players in diverse biological processes including the chemoresistance of cancers. Methods A RNA-seq-based miR-omic analysis of osteosarcoma (OS) cells was performed to detect the levels of miR-34a-5p. Bioinformatics analysis revealed that AGTR1 is one of the target genes of miR-34a-5p...
Medical University, Hefei, 230031, Anhui, ChinaYouguang Pu, Fangfang Zhao & Shanbao CaiXinxiang Medical University, Xinxiang, Henan, 453000, ChinaYinpeng Li, Mingda Cui & Shanbao CaiDepartment of Clinical ... Medical University, Hefei, 230031, Anhui, ChinaXianghui Meng & Shanbao Cai AuthorsSearch for Youguang Pu in:PubMed • Google Scholar Search for Fangfang Zhao in:PubMed • Google Scholar Search for Yinpeng
The Taihu (Tai lake) region is one of the most economically prospering areas of China. Due to its location within this district of high anthropogenic activities, Taihu represents a drastic example of water pollution with nutrients (nitrogen, phosphate), organic contaminants and heavy metals. High nutrient levels combined with very shallow water create large eutrophication...
Cai 1 4 0 Youguang Pu , Qiyi Yi and Fangfang Zhao contributed 1 Department of Orthopedic Surgery, Anhui Cancer Hospital, West District of Affiliated Provincial Hospital of Anhui Medical University
future studies should pay greater attention to examining how KIF26B is regulated in OS or other human tumors. Notes Youguang Pu, Qiyi Yi and Fangfang Zhao contributed equally to this work
-193a-3p and miR-193a-; 5p; Osteosarcoma; Metastasis - Youguang Pu and Fangfang Zhao have contributed equally to this work. Introduction Osteosarcoma is the most common primary bone malignancy in
PIN-FORMED 1 (PIN1) is an important secondary transporter and determines the direction of intercellular auxin flow. As PIN1 performs the conserved function of auxin transport, it is expected that the sequence and structure of PIN1 is conserved. Therefore, we hypothesized that PIN1 evolve under pervasive purifying selection in the protein-coding sequences in angiosperm. To test...
