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Injectable silicone rubber for ocular implantation after evisceration

. Ethical approval form. (PDF) Author Contributions Data curation: Peng Fei Zheng, Hong Yan Deng. Formal analysis: Peng Fei Zheng. Funding acquisition: Qi Sheng You, Xiao Yan Peng. Investigation: Hong ... : Qi Sheng You. Conceptualization: Peng Fei Zheng, Qian Li, Hong Yan Deng, Xiao Yan Peng. Writing ± review & editing: Qi Sheng You, Ian Y. H. Wong, Xiao Yan Peng. 9 / 10 1. Perman KI , Baylis HI

Improvement of the catalytic efficiency of a hyperthermophilic xylanase from Bispora sp. MEY-1

Zheng, Yuan Wang. Data curation: Xiaoyu Wang, Xiangming Xie, Huiying Luo. Formal analysis: Xiaoyu Wang, Fei Zheng, Tao Tu. Funding acquisition: Bin Yao, Huiying Luo. Methodology: Xiaoyu Wang, Shuai You ... Agriculture Research System (no. CARS-42). We would like to thank LetPub for providing linguistic assistance during the preparation of this manuscript. Author Contributions Conceptualization: Xiaoyu Wang, Fei

Genetic mapping of QTL for maize leaf width combining RIL and IF2 populations

Conceptualization: Qingchang Meng. Data curation: Ruixiang Liu. Investigation: Fei Zheng. Methodology: Lingjie Kong. Writing ± original draft: Ruixiang Liu. Writing ± review & editing: Jianhua Yuan, Thomas

Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury

Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). However, evidence regarding the prognostic effect of the platelet-to-lymphocyte ratio (PLR), a novel systemic inflammation marker, among patients with AKI is scarce. In this study, we investigated the value of the PLR in predicting the outcomes of critically ill patients with AKI...

Plasma metabolomics profiles in rats with acute traumatic brain injury

Cui. Software: Yi-Fu Zeng. Supervision: Jie-Kun Luo, Peng Sun, Han-Jin Cui. Validation: Han-Jin Cui. Visualization: Jie-Kun Luo, Peng Sun. Writing ± original draft: Fei Zheng. Writing ± review

Choroidal thickness in school children: The Gobi Desert Children Eye Study

Purpose To investigate choroidal thickness (CT) and its associations in children in a school-based study. Methods The cross-sectional school-based Gobi Desert Children Eye Study included 1565 out of 1911 (81.9%) eligible children from all schools in the oasis region of Ejina in the Gobi Desert. A detailed ophthalmic examination was performed, including spectral-domain optical...

Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng

, Shanghai, 200240, ChinaShanshan Yu & Yan FengJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, 130117, ChinaShanshan Yu, Chunchun Xu, Fei Zheng, Jing Li, Huanxi Zhao, Yulin Dai ... • PubMed • Google Scholar Search for Chunchun Xu in:Nature Research journals • PubMed • Google Scholar Search for Fei Zheng in:Nature Research journals • PubMed • Google Scholar Search for Jing Li

In Vitro Anti-Inflammatory Effects of Three Fatty Acids from Royal Jelly

Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we...

In Vitro Anti-Inflammatory Effects of Three Fatty Acids from Royal Jelly

Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we...

Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature

A review of studies on the body fluid levels of neuroactive amino acids, including glutamate, glutamine, taurine, gamma-aminobutyric acid (GABA), glycine, tryptophan, d-serine, and others, in autism spectrum disorders (ASD) is given. The results reported in the literature are generally inconclusive and contradictory, but there has been considerable variation among the previous...

Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia–reperfusion injury

Aims To investigate whether vascular endothelial growth factor B (VEGF-B) improves myocardial survival and cardiac stem cell (CSC) function in the ischemia–reperfusion (I/R) heart and promotes CSC mobilization and angiogenesis. Methods and results One hour after myocardial ischemia and infarction, rats were treated with recombinant human VEGF-B protein following 24 h or 7 days of...

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice

Autism spectrum disorders (ASDs) are a group of neurodevelopmental afflictions characterized by repetitive behaviors, deficits in social interaction, and impaired communication skills. For most ASD patients, the underlying causes are unknown. Genetic mutations have been identified in about 25 percent of ASD cases, including mutations in epigenetic regulators, suggesting that...

Pseudo-immortalization of postnatal cochlear progenitor cells yields a scalable cell line capable of transcriptionally regulating mature hair cell genes

information Author notesBrandon J. Walters, Shiyong Diao & Fei Zheng These authors contributed equally to this work. AffiliationsDept. of Developmental Neurobiology, St. Jude Children’s Research Hospital ... , Memphis, TN 38105, USABrandon J. Walters, Shiyong Diao, Fei Zheng, Bradley J. Walters, Wanda S. Layman & Jian Zuo AuthorsSearch for Brandon J. Walters in:Nature Research journals • PubMed • Google

PEP-1-SOD1 fusion proteins block cardiac myofibroblast activation and angiotensin II-induced collagen production

Background Oxidative stress is closely associated with cardiac fibrosis. However, the effect of copper, zinc-superoxide dismutase (SOD1) as a therapeutic agent is limited due to the insufficient transduction. This study was aimed to investigate the effect of PEP-1-SOD1 fusion protein on angiotensin II (ANG II)-induced collagen metabolism in rat cardiac myofibroblasts (MCFs...

Protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis

. Based on our results, further human and animal studies are needed to give clearer evidence of L-carnitine in relation to male infertility. Compliance with ethics guidelines Bin ZHU, Yan-fei ZHENG, Yue

Perfluorooctanoic acid exposure for 28 days affects glucose homeostasis and induces insulin hypersensitivity in mice

, P.R. ChinaXuejiang Guo AuthorsSearch for Shengmin Yan in:Nature Research journals • PubMed • Google ScholarSearch for Hongxia Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Fei ... Zheng in:Nature Research journals • PubMed • Google ScholarSearch for Nan Sheng in:Nature Research journals • PubMed • Google ScholarSearch for Xuejiang Guo in:Nature Research journals • PubMed • Google

A Novel Strong Tracking Fault Prognosis Algorithm

Improving the ability to track abruptly changing states and resolving the degeneracy are two difficult problems to particle filter applied to fault prognosis. In this paper, a novel strong tracking fault prognosis algorithm is proposed to settle the above problems. In the proposed algorithm, the artificial immunity algorithm is first introduced to resolve the degeneracy problem...

Intracameral Interleukin 1β, 6, 8, 10, 12p, Tumor Necrosis Factor α and Vascular Endothelial Growth Factor and Axial Length in Patients with Cataract

Objective To assess associations between the aqueous humour concentration of interleukin IL-1β, IL-6, IL-8, IL-10 and IL-12p, tumor necrosis factor α (TNF-α) and vascular endothelial growth factor (VEGF) and axial length in eyes with cataract. Methods The hospital-based investigation included patients who underwent cataract surgery between March 2014 and April 2014. Using aqueous...

Function of Ca2+-/calmodulin-dependent protein kinase IV in Ca2+-stimulated neuronal signaling and behavior

The activity of Ca2+/calmodulin-dependent protein kinase IV (CaMKIV) is sensitive to activity-dependent changes in the level of intracellular Ca2+. Following neuronal stimulation, the activation of CaMKIV may trigger synaptic modifications and transcriptional responses, both of which are involved in regulating cognitive and emotional behavior. Here, we used CaMKIV knockout (KO...