Advanced search    

Search: authors:"Fei Zheng"

38 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature

A review of studies on the body fluid levels of neuroactive amino acids, including glutamate, glutamine, taurine, gamma-aminobutyric acid (GABA), glycine, tryptophan, d-serine, and others, in autism spectrum disorders (ASD) is given. The results reported in the literature are generally inconclusive and contradictory, but there has been considerable variation among the previous...

PEP-1-SOD1 fusion proteins block cardiac myofibroblast activation and angiotensin II-induced collagen production

Background Oxidative stress is closely associated with cardiac fibrosis. However, the effect of copper, zinc-superoxide dismutase (SOD1) as a therapeutic agent is limited due to the insufficient transduction. This study was aimed to investigate the effect of PEP-1-SOD1 fusion protein on angiotensin II (ANG II)-induced collagen metabolism in rat cardiac myofibroblasts (MCFs...

3D Cardiac microvessels embolization imaging based on X-ray phase contrast imaging

Background The treatment of microcirculatory impairment will have great impact if it can be applied to myocardial infarction (MI) patients. The problem is how to study these tiny structures and microphenomenon in heart. Methods We investigated the visualization of cardiac microvessels embolization by the mean of X-ray phase contrast imaging (XPCI), which is a recently emerged...

Prognostic value of platelet-to-lymphocyte ratios among critically ill patients with acute kidney injury

Inflammation plays an important role in the initiation and progression of acute kidney injury (AKI). However, evidence regarding the prognostic effect of the platelet-to-lymphocyte ratio (PLR), a novel systemic inflammation marker, among patients with AKI is scarce. In this study, we investigated the value of the PLR in predicting the outcomes of critically ill patients with AKI...

Effect of the Random Error on the Radiation Characteristic of the Reflector Antenna Based on Two-Dimensional Fractal

Influence of the random error due to the distortion of the antenna reflector was discussed by using the two-dimensional fractal model. Firstly, a mathematical model of the random error was presented to investigate its impact on the radiation characteristic of the antenna, which was filtered from the two-dimensional fractal by using the wavelet analysis method. Based on the error...

Relationship between toll-like receptor 4 levels in aorta and severity of atherosclerosis

Objective To investigate the relationship between levels of toll-like receptor 4 (TLR4) protein in aortic tissue and the severity of atherosclerosis in patients undergoing coronary artery bypass graft (CABG) surgery.

Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia–reperfusion injury

Aims To investigate whether vascular endothelial growth factor B (VEGF-B) improves myocardial survival and cardiac stem cell (CSC) function in the ischemia–reperfusion (I/R) heart and promotes CSC mobilization and angiogenesis. Methods and results One hour after myocardial ischemia and infarction, rats were treated with recombinant human VEGF-B protein following 24 h or 7 days of...

PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways

Background Catalase (CAT) breaks down H2O2 into H2O and O2 to protects cells from oxidative damage. However, its translational potential is limited because exogenous CAT cannot enter living cells automatically. This study is aimed to investigate if PEP-1-CAT fusion protein can effectively protect cardiomyocytes from oxidative stress due to hypoxia/reoxygenation (H/R)-induced...

The combined transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury

Background Our previous studies indicate that either PEP-1-superoxide dismutase 1 (SOD1) or PEP-1-catalase (CAT) fusion proteins protects myocardium from ischemia-reperfusion-induced injury in rats. The aim of this study is to explore whether combined use of PEP-1-SOD1 and PEP-1-CAT enhances their protective effects. Methods SOD1, PEP-1-SOD1, CAT or PEP-1-CAT fusion proteins were...

Protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis

. Based on our results, further human and animal studies are needed to give clearer evidence of L-carnitine in relation to male infertility. Compliance with ethics guidelines Bin ZHU, Yan-fei ZHENG, Yue

Subsumption resolution: an efficient and effective technique for semi-naive Bayesian learning

Fei Zheng Geoffrey I. Webb Pramuditha Suraweera Liguang Zhu Editors: Mark Craven and Johannes Frnkranz. Semi-naive Bayesian techniques seek to improve the accuracy of naive Bayes (NB) by relaxing

Learning by extrapolation from marginal to full-multivariate probability distributions: decreasingly naive Bayesian classification

Averaged n-Dependence Estimators (AnDE) is an approach to probabilistic classification learning that learns by extrapolation from marginal to full-multivariate probability distributions. It utilizes a single parameter that transforms the approach between a low-variance high-bias learner (Naive Bayes) and a high-variance low-bias learner with Bayes optimal asymptotic error. It...

A Novel Strong Tracking Fault Prognosis Algorithm

Improving the ability to track abruptly changing states and resolving the degeneracy are two difficult problems to particle filter applied to fault prognosis. In this paper, a novel strong tracking fault prognosis algorithm is proposed to settle the above problems. In the proposed algorithm, the artificial immunity algorithm is first introduced to resolve the degeneracy problem...

In Vitro Anti-Inflammatory Effects of Three Fatty Acids from Royal Jelly

Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we...

In Vitro Anti-Inflammatory Effects of Three Fatty Acids from Royal Jelly

Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we...

Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice

; Published 4 June 2014 Academic Editor: Tânia Silvia Fröde Copyright © 2014 Fei Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing

Gong,1 Shanshan Xing,2 Fei Zheng,1 and Qichong Xing1 1Department of Cardiology, Qianfoshan Hospital, Shandong University, 16766 Jingshi Road, Jinan 250014, China 2Department of Cardiology, Shandong

Adenovirus-mediated stromal cell-derived factor-1 alpha gene transfer improves cardiac structure and function after experimental myocardial infarction through angiogenic and antifibrotic actions

Stromal cell-derived factor 1α (SDF-1) is not only a major chemotactic factor, but also an inducer of angiogenesis. The effects of SDF-1α on the left ventricular remodeling in a rat myocardial infarction (MI) model were analyzed. Myocardial infarction was induced by ligation of the left coronary artery in rats. 0.5 × 1010 pfu/ml AdV-SDF-1 or 0.5 × 1010 pfu/ml Adv-LacZ were...

Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway

The transforming growth factor-β (TGF-β) signalling pathway participates in various biological processes. Dysregulation of Smad4, a central cellular transducer of TGF-β signalling, is implicated in a wide range of human diseases and developmental disorders. However, the mechanisms underlying Smad4 dysregulation are not fully understood. Using a functional screening approach based...

Injectable silicone rubber for ocular implantation after evisceration

. Ethical approval form. (PDF) Author Contributions Data curation: Peng Fei Zheng, Hong Yan Deng. Formal analysis: Peng Fei Zheng. Funding acquisition: Qi Sheng You, Xiao Yan Peng. Investigation: Hong ... : Qi Sheng You. Conceptualization: Peng Fei Zheng, Qian Li, Hong Yan Deng, Xiao Yan Peng. Writing ± review & editing: Qi Sheng You, Ian Y. H. Wong, Xiao Yan Peng. 9 / 10 1. Perman KI , Baylis HI