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Search: authors:"Francesca Puledda"

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An update on migraine: current understanding and future directions

Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the ...

Current Approaches to Neuromodulation in Primary Headaches: Focus on Vagal Nerve and Sphenopalatine Ganglion Stimulation

number of ongoing studies and the real possibility to add these exciting methods to their practice. Compliance with Ethical Standards Conflict of Interest Francesca Puledda declares no conflict of interest

Topiramate modulates habituation in migraine: evidences from nociceptive responses elicited by laser evoked potentials

Background Lack of habituation during repetitive stimulation is the most consistent interictal abnormality of cortical information processing observed in migraine. Preventive migraine treatments might act by stabilizing cortical excitability level and thus the habituation to external stimuli. Methods We examined the effects of preventive treatment with topiramate on migraineur’s ...