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Search: authors:"Frederic Billings"

2 papers found.
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Acute kidney injury following cardiac surgery: current understanding and future directions

Acute kidney injury (AKI) complicates recovery from cardiac surgery in up to 30 % of patients, injures and impairs the function of the brain, lungs, and gut, and places patients at a 5-fold increased risk of death during hospitalization. Renal ischemia, reperfusion, inflammation, hemolysis, oxidative stress, cholesterol emboli, and toxins contribute to the development and...

Coenzyme Q 10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress

Background Coenzyme Q 10 (CoQ 10 ) supplementation improves mitochondrial coupling of respiration to oxidative phosphorylation, decreases superoxide production in endothelial cells, and may improve functional cardiac capacity in patients with congestive heart failure. There are no studies evaluating the safety, tolerability and efficacy of varying doses of CoQ 10 in chronic...