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One-year survival rate and healthcare costs after cardiac arrest in Taiwan, 2006–2012

speakers of English. For a certificate, please see: http://www.textcheck.com/certificate/Iz72Yl. Author Contributions Conceptualization: Yi-Ming Weng, Cheng-Yu Chien, Kuan-Fu Chen, Jr-Rung Lin, Chee-Jen ... Chien. Software: Jr-Rung Lin, Chee-Jen Chang. Supervision: Chen-June Seak, Kuan-Fu Chen. Validation: Jr-Rung Lin. Writing ± original draft: Yi-Ming Weng, Cheng-Yu Chien. Writing ± review & editing

Sequencing of complete mitochondrial genomes confirms synonymization of Hyalomma asiaticum asiaticum and kozlovi, and advances phylogenetic hypotheses for the Ixodidae

-Feng Liu, Chuang-Fu Chen. Data curation: Zhi-Qiang Liu, Deng-Feng Wang, Jun-Wei Wang, Tao Han, Chen-Feng Shen. Formal analysis: Zhi-Qiang Liu, Li Zhao, Tao Han, Yuan-Zhi Wang. Funding acquisition: Zhi ... Chen, Chuang-Fu Chen. Resources: Zhi-Qiang Liu, Nuer Kuermanali, Chen-Feng Shen. Software: Yan-Feng Liu, Jie Wang. Supervision: Zhuang-Zhi Zhang, Chuang-Fu Chen. Validation: Zhi-Qiang Liu, Jun-Wei

HawkRank: a new scoring function for protein–protein docking based on weighted energy terms

Deciphering the structural determinants of protein–protein interactions (PPIs) is essential to gain a deep understanding of many important biological functions in the living cells. Computational approaches for the structural modeling of PPIs, such as protein–protein docking, are quite needed to complement existing experimental techniques. The reliability of a protein–protein...

Effects of decades of physical driving on body movement and motion sickness during virtual driving

. Stoffregen. Formal analysis: Thomas A. Stoffregen, Chih-Hui Chang. Investigation: Fu-Chen Chen, Wei-Jhong Zeng. Methodology: Thomas A. Stoffregen, Chih-Hui Chang. Supervision: Thomas A. Stoffregen, Chih

Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage

Inflammatory responses significantly contribute to neuronal damage and poor functional outcomes following intracerebral hemorrhage (ICH). Soluble epoxide hydrolase (sEH) is known to induce neuroinflammatory responses via degradation of anti-inflammatory epoxyeicosatrienoic acids (EET), and sEH is upregulated in response to brain injury. The present study investigated the...

Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage

Inflammatory responses significantly contribute to neuronal damage and poor functional outcomes following intracerebral hemorrhage (ICH). Soluble epoxide hydrolase (sEH) is known to induce neuroinflammatory responses via degradation of anti-inflammatory epoxyeicosatrienoic acids (EET), and sEH is upregulated in response to brain injury. The present study investigated the...

Morphological and molecular divergence of Rhipicephalus turanicus tick from Albania and China

Rhipicephalus turanicus is an important tick species potentially carrying tick-borne pathogens. Several tick species have obvious subspecies divergence. However few studies aimed to examine the existence of divergence within R. turanicus. Therefore, a detailed morphological and molecular analysis was conducted for comparing R. turanicus from the Mediterranean Basin (represented...

Detection of Plasma Biomarkers Using Immunomagnetic Reduction: A Promising Method for the Early Diagnosis of Alzheimer’s Disease

also holds MagQu stock. Ming-Jang Chiu and Ta-Fu Chen have nothing to disclose. Compliance with Ethics Guidelines. This article is based on previously conducted studies and does not involve any new

Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnosis. We present a novel silicon-based nanostructured microfluidics platform named as “Cell Reveal™” to...

Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnosis. We present a novel silicon-based nanostructured microfluidics platform named as “Cell Reveal™” to...

Comparative analyses of structural features and scaffold diversity for purchasable compound libraries

Large purchasable screening libraries of small molecules afforded by commercial vendors are indispensable sources for virtual screening (VS). Selecting an optimal screening library for a specific VS campaign is quite important to improve the success rates and avoid wasting resources in later experimental phases. Analysis of the structural features and molecular diversity for...

Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C-reactive protein: a systematic review and meta-analysis

Background The soluble cluster of differentiation 14 (or presepsin) is a free fragment of glycoprotein expressed on monocytes and macrophages. Although many studies have been conducted recently, the diagnostic performance of presepsin for sepsis remains debated. We performed a systematic review and meta-analysis of the available literature to assess the accuracy of presepsin for...

Critical factors influencing physicians’ intention to use computerized clinical practice guidelines: an integrative model of activity theory and the technology acceptance model

and the technology acceptance model Ju-Ling Hsiao 2 Rai-Fu Chen 0 1 0 Department of Information Management, Chia-Nan University of Pharmacy and Science , No.60, Sec. 1, Erren Rd., Rende Dist., Tainan ... , Telemedicine and e-Health, and Total Quality Management & Business Excellence. Rai-Fu Chen is an associate professor of department of Information Management at the Chia-Nan University of Pharmacy and Science

Differential regulation of interleukin-8 and human beta-defensin 2 in Pseudomonas aeruginosa-infected intestinal epithelial cells

Fu-Chen Huang 0 0 Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine , 123, Ta-pei Road, Niao-sung District, Kaohsiung , Taiwan

Evaluation of a novel biodegradable thermosensitive keto-hydrogel for improving postoperative pain in a rat model

Guo, Chang-Jhih Cai, Chiu-Yen Chung. Formal analysis: Meng-Huang Wu, Ming-Hung Shih, Wei-Bin Hsu, Navneet Kumar Dubey, Tsai-Yu Lin, Meng-Yow Hsieh, Chin-Fu Chen, Chung-Sheng Shi, Ren-Shyang Guo, Chang ... -Hung Shih, Wei-Bin Hsu, Navneet Kumar Dubey, Wen-Fu Lee, Tsai-Yu Lin, Meng-Yow Hsieh, Chin-Fu Chen, Kuo-Ti Peng, Tsung-Jen Huang, Chung-Sheng Shi, Ren-Shyang Guo, Chang-Jhih Cai, Chiu-Yen Chung

Anti-inflammatory effect of resveratrol in human coronary arterial endothelial cells via induction of autophagy: implication for the treatment of Kawasaki disease

Background Kawasaki disease (KD) is an acute febrile vasculitis in childhood, which is the leading cause of acquired heart disease in children. If untreated, KD can result in coronary aneurysms in 25% of patients, and even under intravenous immunoglobulin (IVIG) treatment, 10–20% of children will have IVIG resistance and increased risk of developing coronary arteritis...

Vertebral artery terminating in posterior inferior cerebellar artery: A normal variation with clinical significance

A vertebral artery (VA) terminating in a posterior inferior cerebellar artery (PICA) is often considered to be a normal variation associated with VA hypoplasia. We aimed to investigate the clinical significance of this cerebrovascular variant. A total of 80 patients with clinically evident cerebrovascular events in posterior circulation were examined by duplex sonography and...

Using controlled attenuation parameter combined with ultrasound to survey non-alcoholic fatty liver disease in hemodialysis patients: A prospective cohort study

Background and aims Controlled attenuation parameter (CAP) is a non-invasive method for measuring hepatic steatosis (HS). Non-alcoholic fatty liver disease (NAFLD) is closely related to cardiovascular diseases (CVDs). CVDs are the leading cause of morbidity and mortality in hemodialysis patients. The aim of this study was to investigate the prevalence of NAFLD in hemodialysis...

The magnitude and mechanisms of the weekend effect in hospital admissions: A protocol for a mixed methods review incorporating a systematic review and framework synthesis

Background Growing literature has demonstrated that patients admitted to hospital during weekends tend to have less favourable outcomes, including increased mortality, compared with similar patients admitted during weekdays. Major policy interventions such as the 7-day services programme in the UK NHS have been initiated to reduce this weekend effect, although the mechanisms...

Comorbidity and dementia: A nationwide survey in Taiwan

Background Comorbid medical diseases are highly prevalent in the geriatric population, imposing hardship on healthcare services for demented individuals. Dementia also complicates clinical care for other co-existing medical conditions. This study investigated the comorbidities associated with dementia in the elderly population aged 65 years and over in Taiwan. Methods We...