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Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression

Non-coding RNAs (ncRNAs) have been shown to regulate gene expression involved in tumor progression of multiple malignancies. Our previous studies indicated that large tumor suppressor kinase 1 (LATS1), a core part of Hippo signaling pathway, functions as a tumor suppressor in gastric cancer (GC). But, the underlying molecular mechanisms by which ncRNAs modulate LATS1 expression in ...

Anaplastic lymphoma kinase-positive large B-cell lymphoma: Clinico-pathological study of 17 cases with review of literature

We retrospectively analysed 17 cases of anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+, LBCL) according to the morphological, immunohistochemical, molecular and clinical features, using which we intend to elucidate the clinicopathological characteristics of this rare entity. In this study, all cases de facto share common features that defined them as a single ...

Ethnic Multilingual Education in China: A Critical Observation

reviewers of this paper. Dr. Ge Wang is currently an English professor of applied linguistics of the School of Foreign Languages, Yunnan University, China. His areas of study are bi/trilingual education

Experimental Study on Thermal Conductivity and Hardness of Cu and Ni Nanoparticle Packed Bed for Thermoelectric Application

The hot-wire method is applied in this paper to probe the thermal conductivity (TC) of Cu and Ni nanoparticle packed beds (NPBs). A different decrease tendency of TC versus porosity than that currently known is discovered. The relationship between the porosity and nanostructure is investigated to explain this unusual phenomenon. It is found that the porosity dominates the TC of the ...

Spectral X-Ray CT Image Reconstruction with a Combination of Energy-Integrating and Photon-Counting Detectors

The purpose of this paper is to develop an algorithm for hybrid spectral computed tomography (CT) which combines energy-integrating and photon-counting detectors. While the energy-integrating scan is global, the photon-counting scan can have a local field of view (FOV). The algorithm synthesizes both spectral data and energy-integrating data. Low rank and sparsity prior is used for ...

Influence of Nanopore Shapes on Thermal Conductivity of Two-Dimensional Nanoporous Material

-Xin Zhang 0 Ge Wang 2 0 School of Mechanical Engineering, University of Science and Technology Beijing , Beijing 100083 , China 1 School of Electric Power Engineering, China University of Mining and

Meerkat

Ge Wang Iowa State University Copyright c 2013 by the authors. Sketch is produced by The Berkeley Electronic Press (bepress). http://lib.dr.iastate.edu/sketch - 2013 Meerkat

A New 3D Coordination Polymer Based on Pentanuclear Cd(II) Rod-Shaped Secondary Building Unit: Synthesis, Crystal Structure and Luminescent Property

Hua-Rui Wang 0 Jian-Ge Wang 0 0 H.-R. Wang (&) J.-G. Wang College of Chemistry and Chemical Engineering, Luoyang Normal University , Luoyang 471022, People A new coordination polymer [Cd2.5(l3OH)(L

Using a Mixed Model to Evaluate Job Satisfaction in High-Tech Industries

R&D professionals are the impetus behind technological innovation, and their competitiveness and capability drive the growth of a company. However, high-tech industries have a chronic shortage of such indispensable professionals. Accordingly, reducing R&D personnel turnover has become a major human resource management challenge facing innovative companies. This study combined ...

Deciphering Transcriptome and Complex Alternative Splicing Transcripts in Mammary Gland Tissues from Cows Naturally Infected with Staphylococcus aureus Mastitis

Alternative splicing (AS) contributes to the complexity of the mammalian proteome and plays an important role in diseases, including infectious diseases. The differential AS patterns of these transcript sequences between the healthy (HS3A) and mastitic (HS8A) cows naturally infected by Staphylococcus aureus were compared to understand the molecular mechanisms underlying mastitis ...

MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling

Background MicroRNAs (miRNAs) have been proved involved in many tumorigenic behaviors including tumor growth. But, the clinical significance and functions of miRNA-203 in gastric cancer (GC) remain elusive. Results Decreased expression of miRNA-203 was correlated with tumor size, poor prognosis and recurrence in GC patients. Overexpression of miR-203 or knockdown of its target ...

Dynamic Bowtie Filter for Cone-Beam/Multi-Slice CT

A pre-patient attenuator (“bowtie filter” or “bowtie”) is used to modulate an incoming x-ray beam as a function of the angle of the x-ray with respect to a patient to balance the photon flux on a detector array. While the current dynamic bowtie design is focused on fan-beam geometry, in this study we propose a methodology for dynamic bowtie design in multi-slice/cone-beam geometry. ...

Development of maizeSNP3072, a high-throughput compatible SNP array, for DNA fingerprinting identification of Chinese maize varieties

Single nucleotide polymorphisms (SNPs) are abundant and evenly distributed throughout the maize (Zea mays L.) genome. SNPs have several advantages over simple sequence repeats, such as ease of data comparison and integration, high-throughput processing of loci, and identification of associated phenotypes. SNPs are thus ideal for DNA fingerprinting, genetic diversity analysis, and ...

One-Carbon Metabolic Factors and Risk of Renal Cell Cancer: A Meta-Analysis

Background Nutrients related to one-carbon metabolism were previously shown to be significantly associated with the risk of cancer. The aim of this meta-analysis was to evaluate potential relationships between one-carbon metabolic factors and renal cell cancer (RCC) risk. Methods PubMed, EMBASE, and Cochrane Library databases were searched through March 2015 for observational ...

Unsupervised Deconvolution of Dynamic Imaging Reveals Intratumor Vascular Heterogeneity and Repopulation Dynamics

With the existence of biologically distinctive malignant cells originated within the same tumor, intratumor functional heterogeneity is present in many cancers and is often manifested by the intermingled vascular compartments with distinct pharmacokinetics. However, intratumor vascular heterogeneity cannot be resolved directly by most in vivo dynamic imaging. We developed ...

Endoplasmic Reticulum Stress Mediates the Anti-Inflammatory Effect of Ethyl Pyruvate in Endothelial Cells

Ethyl pyruvate (EP) is a simple aliphatic ester of the metabolic intermediate pyruvate that has been demonstrated to be a potent anti-inflammatory agent in a variety of in vivo and in vitro model systems. However, the protective effects and mechanisms underlying the actions of EP against endothelial cell (EC) inflammatory injury are not fully understood. Previous studies have ...

High-incidence of PTEN mutations in Chinese patients with primary small cell carcinoma of the esophagus

Yang 0 Dong Wang 0 Zengpeng Li Ge Wang 0 0 Cancer Center, Institute of Surgical Research, Daping Hospital, Third Military Medical University , Chongqing 400042 , China Background: Primary small cell