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. Biochemical and adaptive behavior data from ASD, NEU, and SIB participants. (CSV) Conceptualization: Genyuan Li, Herschel Rabitz. Data curation: Genyuan Li, Olivia Lee. Formal analysis: Genyuan Li, Olivia Lee ... , Herschel Rabitz. Funding acquisition: Genyuan Li, Herschel Rabitz. Investigation: Genyuan Li, Olivia Lee, Herschel Rabitz. Methodology: Genyuan Li, Herschel Rabitz. Project administration: Herschel
The analysis of gene network robustness to noise and mutation is important for fundamental and practical reasons. Robustness refers to the stability of the equilibrium expression state of a gene network to variations of the initial expression state and network topology. Numerical simulation of these variations is commonly used for the assessment of robustness. Since there exists a ...
This work presents an adapted Random Sampling - High Dimensional Model Representation (RS-HDMR) algorithm for synergistically addressing three key problems in network biology: (1) identifying the structure of biological networks from multivariate data, (2) predicting network response under previously unsampled conditions, and (3) inferring experimental perturbations based on the ...