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HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens

Camilla Götz Thomas P. Schmidt Gernot Posselt Silja Wessler 0 Equal contributors Division of Microbiology, Department of Molecular Biology, Paris-Lodron University of Salzburg , Billroth Str. 11, A-5020

The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis

Infections with the human pathogen Helicobacter pylori (H. pylori) can lead to severe gastric diseases ranging from chronic gastritis and ulceration to neoplastic changes in the stomach. Development and progress of H. pylori-associated disorders are determined by multifarious bacterial factors. Many of them interact directly with host cells or require specific receptors, while ...