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Academic Education in Complementary Medicine: A Tuscan Methodological Perspective

, Italy Copyright © 2007 Gian Franco Gensini and Andrea A. Conti. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use

Marfan syndrome: current perspectives

Marfan syndrome: current perspectives Guglielmina Pepe,1,2 Betti Giusti,1,2 Elena Sticchi,1,2 Rosanna Abbate,1,2 Gian Franco Gensini,1–3 Stefano Nistri2,4 1Department of Experimental and Clinical

Luigi Pagliaro, Marco Bobbio, Agostino Colli: Diagnosis in Medicine

0 D. Prisco (&) G. F. Gensini Department of Medical and Surgical Critical Care, University of Florence , Viale Morgagni 85, 50134 Florence, Italy Gian Franco Gensini - Although devoted to

Urban-Hazard Risk Analysis: Mapping of Heat-Related Risks in the Elderly in Major Italian Cities

Background Short-term impacts of high temperatures on the elderly are well known. Even though Italy has the highest proportion of elderly citizens in Europe, there is a lack of information on spatial heat-related elderly risks. Objectives Development of high-resolution, heat-related urban risk maps regarding the elderly population (≥65). Methods A long time-series (2001–2013) of...

Editor-in-Chief: thank you and farewell

Gian Franco Gensini 0 0 G. F. Gensini (&) Editor-in-Chief, Internal and Emergency Medicine, Department of Critical Care Medicine and Surgery, University of Florence and Azienda Ospedaliero

The fourth year of Internal and Emergency Medicine

Gian Franco Gensini 0 0 G. F. Gensini (&) Editor-in-Chief, Internal and Emergency Medicine, Department of Critical Care Medicine and Surgery, University of Florence and Azienda Ospedaliero

Pre-participation assessment in young athletes: a state affair

One of the main goals for maintaining “wellness” is to promote and sustain physical activity as an “habitual practice”. In both moderate and more vigorous forms, it normally generates numerous and well-known benefits in both young and not-so-young subjects [2]. More recently, sports activity, either in a competitive or non-competitive form, has started to involve a larger group...

H3M2: detection of runs of homozygosity from whole-exome sequencing data

Motivation: Runs of homozygosity (ROH) are sizable chromosomal stretches of homozygous genotypes, ranging in length from tens of kilobases to megabases. ROHs can be relevant for population and medical genetics, playing a role in predisposition to both rare and common disorders. ROHs are commonly detected by single nucleotide polymorphism (SNP) microarrays, but attempts have been...

Beyond the unmeasured anions: the clinics

Chiara Lazzeri 0 Serafina Valente 0 Gian Franco Gensini 0 0 C. Lazzeri (&) S. Valente G. F. Gensini Intensive Cardiac Care Unit , Florence, Italy Conflict of interest None. - We thank Dr Berend

Commentary on: Economic evaluation of human papilloma virus vaccination in the European Union: a critical review

The article by Koleva et al. [1] in current issue is unusual reading for the public of IEM. First, systematic reviews of economic evaluations are still uncommon in general medical journals. Second, this review on HPV vaccination deals with a very important public health topic, which, on the other hand, is not a typical theme for this journal.There are good reasons for the...

Contact forces during hybrid atrial fibrillation ablation: an in vitro evaluation

Purpose Data on epicardial contact force efficacy in dual epicardial–endocardial atrial fibrillation ablation procedures are lacking. We present an in vitro study on the importance of epicardial and endocardial contact forces during this procedure. Methods The in vitro setup consists of two separate chambers, mimicking the endocardial and epicardial sides of the heart. A circuit...

Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction

Since cardiorenal dysfunction is usually secondary to multiple factors acting in concert (and not only reduced cardiac output) in the present paper we are going to focus on the interrelationship between heart failure with normal ejection fraction and the development of cardiorenal syndrome. The coexistence of renal impairment in heart failure with preserved ejection fraction (CRS...

The Impact of Hypertension on Patients with Acute Coronary Syndromes

Arterial chronic hypertension (HTN) is a well-known cardiovascular risk factor for development of atherosclerosis. In order to explain the relation between HTN and acute coronary syndromes the following factors should be considered: (1) risk factors are shared by the diseases, such as genetic risk, insulin resistance, sympathetic hyperactivity, and vasoactive substances (i.e...

Minimally invasive thoracoscopic hybrid treatment of lone atrial fibrillation: early results of monopolar versus bipolar radiofrequency source

We compare results of a hybrid monopolar vs. a hybrid bipolar thoracoscopic approach employing radiofrequency (RF) sources for the surgical treatment of lone atrial fibrillation (LAF). From January 2008 to June 2010, 19 patients (35.1%) underwent RF monopolar/monolateral RF ablation, whereas 35 (64.9%) had RF bipolar/bilateral thoracoscopic ablation. One-year time-related...

EXCAVATOR: detecting copy number variants from whole-exome sequencing data

We developed a novel software tool, EXCAVATOR, for the detection of copy number variants (CNVs) from whole-exome sequencing data. EXCAVATOR combines a three-step normalization procedure with a novel heterogeneous hidden Markov model algorithm and a calling method that classifies genomic regions into five copy number states. We validate EXCAVATOR on three datasets and compare the...

Measuring the impact of evidence: the Cochrane systematic review of organised stroke care

available worldwide. Considerable impact in terms of publications, dissemination, policy and behaviour can be elicited for systematic reviews. A clinicians point of view Gian Franco Gensini, Roberto Gusinu