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A review of Neuropathic Pain: From Guidelines to Clinical Practice

publication were also funded by Pfizer, Italy. Giorgio Cruccu and Andrea Truini thank Georgii Filatov of Springer Healthcare Communications who wrote the outline and first draft of this review. This medical ... integrity of the work as a whole, and have given final approval to the version to be published. Disclosures. Giorgio Cruccu has received honorarium from Pfizer, as well as research grant, consulting fees and

l-Acetyl-carnitine in Patients with Carpal Tunnel Syndrome: Effects on Nerve Protection, Hand Function and Pain

Psychiatry, Sapienza University , Viale Universita` 30, 00185 Roma , Italy 2 & Giorgio Cruccu 3 Department of Neuroscience, Rehabilitation , Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI ... of ALFASIGMA Group. Conflict of interest Giorgio Cruccu has received a research grant, consulting fees and payments for lectures from Sigma-Tau of ALFASIGMA Group, and consulting fees from Angelini

Neuropathic Pain: The Scope of the Problem

reinforce the other. ACKNOWLEDGEMENTS This supplement has been sponsored by Pfizer, Italy. The article processing charges for this publication were also funded by Pfizer, Italy. Giorgio Cruccu and Andrea ... to be published. Disclosures. Giorgio Cruccu has received honorarium from Pfizer, as well as research grant, consulting fees and/or payments for lectures from Alfasigma Group, Angelini, Biogen, and

Natural history and outcome of 200 outpatients with classical trigeminal neuralgia treated with carbamazepine or oxcarbazepine in a tertiary centre for neuropathic pain

Background The guidelines on trigeminal neuralgia management that have been agreed and jointly published by the American Academy of Neurology and the European Federation of Neurological Societies recommend carbamazepine (CBZ) and oxcarbazepine (OXC) as the first-choice medical treatments in patients with trigeminal neuralgia (TN). The aim of this retrospective study was to...

Tools for Assessing Neuropathic Pain

Giorgio Cruccu and Andrea Truini discuss a new pain assessment tool published in PLoS Medicine called Standardized Evaluation of Pain and they review other tools to assess neuropathic pain.

Trigeminal isolated sensory neuropathy (TISN) and FOSMN syndrome: despite a dissimilar disease course do they share common pathophysiological mechanisms?

Background Patients presenting with bilateral trigeminal hypoesthesia may go on to have trigeminal isolated sensory neuropathy, a benign, purely trigeminal neuropathy, or facial-onset sensory motor neuronopathy (FOSMN), a malignant life-threatening condition. No diagnostic criteria can yet differentiate the two conditions at their onset. Nor is it clear whether the two diseases...

Topiramate modulates habituation in migraine: evidences from nociceptive responses elicited by laser evoked potentials

Background Lack of habituation during repetitive stimulation is the most consistent interictal abnormality of cortical information processing observed in migraine. Preventive migraine treatments might act by stabilizing cortical excitability level and thus the habituation to external stimuli. Methods We examined the effects of preventive treatment with topiramate on migraineur’s...

Improving the primary care physicians� decision making for fibromyalgia in clinical practice: development and validation of the Fibromyalgia Detection (FibroDetect�) screening tool

Background Fibromyalgia diagnosis is a challenging and long process, especially among primary care physicians (PCPs), because of symptom heterogeneity, co-morbidities and clinical overlap with other disorders. The purpose was to develop and validate a screening tool in French (FR), German (DE) and English (UK) to help PCPs identify patients with fibromyalgia. Methods The...