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mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes

The acute phase response is a systemic reaction to inflammatory processes characterized by multiple physiological adaptations, including the hepatic synthesis of acute-phase proteins. In humans, serum amyloid A (SAA) is one of the most prominent of these proteins. Despite the huge increase of serum levels of SAA in inflammation, its biological role remains to be elucidated, even...

Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane

Histones are the main structural components of the nucleosome, hence targets of many regulatory proteins that mediate processes involving changes in chromatin. The functional outcome of many pathways is “written” in the histones in the form of post-translational modifications that determine the final gene expression readout. As a result, modifications, alone or in combination...

Circadian Rhythms of Sense and Antisense Transcription in Sugarcane, a Highly Polyploid Crop

Milton Yutaka Nishiyama Jr 0 Glaucia Mendes Souza 0 Samuel P. Hazen, University of Massachusetts Amherst, United States of America 0 Departamento de Bioqu mica, Instituto de Qu mica, Universidade de Sa o

Full-Length Enriched cDNA Libraries and ORFeome Analysis of Sugarcane Hybrid and Ancestor Genotypes

Sugarcane is a major crop used for food and bioenergy production. Modern cultivars are hybrids derived from crosses between Saccharum officinarum and Saccharum spontaneum. Hybrid cultivars combine favorable characteristics from ancestral species and contain a genome that is highly polyploid and aneuploid, containing 100–130 chromosomes. These complex genomes represent a huge...

Co-expression network analysis reveals transcription factors associated to cell wall biosynthesis in sugarcane

, Universidade de Sa ̃o Paulo , Sa ̃o Paulo , Brazil 2 & Glaucia Mendes Souza 3 Present Address: Universidade Federal do Recoˆncavo da Bahia , Cruz das Almas , Brazil 4 Centro de Cieˆncias Agra ́rias, Universidade

Identification of sense and antisense transcripts regulated by drought in sugarcane

Sugarcane is an important sugar and energy crop that can be used efficiently for biofuels production. The development of sugarcane cultivars tolerant to drought could allow for the expansion of plantations to sub-prime regions. Knowledge on the mechanisms underlying drought responses and its relationship with carbon partition would greatly help to define routes to increase yield...