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Five-year clinical follow-up of the STENTYS self-apposing stent in complex coronary anatomy: a single-centre experience with report of specific angiographic indications

this device in lesions with vessel diameter variance [ 29 ]. Funding The authors received no specific funding for this work. Conflict of interest H. Lu, R.J. Bekker, M.J. Grundeken, P. Woudstra, J.J

Regulation of spindle integrity and mitotic fidelity by BCCIP

Centrosomes together with the mitotic spindle ensure the faithful distribution of chromosomes between daughter cells, and spindle orientation is a major determinant of cell fate during tissue regeneration. Spindle defects are not only an impetus of chromosome instability but are also a cause of developmental disorders involving defective asymmetric cell division. In this work, we...

Comparison of effectiveness and safety between conbercept and ranibizumab for treatment of neovascular age-related macular degeneration. A retrospective case-controlled non-inferiority multiple center study

, Heilongjiang, PR ChinaJ Cui, H Lu, H Dong, L Wang, D Wei & H ChenDepartment of Orthopedic Surgery and BME-Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, USAJ Cui, Y Jiao & W ... for J Cui in:Nature Research journals • PubMed • Google ScholarSearch for D Sun in:Nature Research journals • PubMed • Google ScholarSearch for H Lu in:Nature Research journals • PubMed • Google

Cadherin 6 is activated by Epstein–Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma

- 247 ( 2014 ). 9. Zeng , L. , Cui , J. , Wu , H. & Lu , Q. The emerging role of circulating microRNAs as biomarkers in autoimmune diseases . Autoimmunity 47 , 419 - 429 ( 2014 ). 10. Deng , X. et al. The

Quasispecies evolution of the prototypical genotype 1 porcine reproductive and respiratory syndrome virus early during in vivo infection is rapid and tissue specific

selection . Proc Natl Acad Sci USA 109 : 12980 - 12985 51. Yu D , Lv J , Sun Z , Zheng H , Lu J , Yuan S ( 2009 ) Reverse genetic manipulation of the overlapping coding regions for structural proteins of the

Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms

Medicine, VU University Medical Center , Amsterdam , The Netherlands 1 T.C. Konings Department of Cardiology, VU University Medical Center , Amsterdam , The Netherlands 2 R.J. de Winter () · M. Nassif · H ... . Lu · B.J. Bouma · B. Straver · N.A. Blom · A.P.C.M. Backx · M. Groenink · S.M. Boekholdt · B.J.M. Mulder Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University

Whole Mitogenomes Reveal the History of Swamp Buffalo: Initially Shaped by Glacial Periods and Eventually Modelled by Domestication

in:Nature Research journals • PubMed • Google Scholar Search for H. Lu in:Nature Research journals • PubMed • Google Scholar Search for L. Caporali in:Nature Research journals • PubMed • Google Scholar

Relationship between atrial septal defects and asthma-like dyspnoea: the impact of transcatheter closure

remains to be further investigated in prospective studies. Funding None. Conflict of interest M. Nassif, C.B.B.C. Heuschen, H. Lu, B.J. Bouma, R.P. van Steenwijk, P.J. Sterk, B.J.M. Mulder and R. J. de

Effect of low irradiance on the photosynthetic performance and spiking of Phalaenopsis

Lowering irradiance can delay the flower stalk, i.e., spike development, in order to schedule flowering time of Phalaenopsis; however, the effect on photosynthetic performance and spiking inhibition remains poorly understood. We compared light and shade treatments of Phalaenopsis aphrodite subsp. formosana in order to determine how limiting light affects day-night changes in the...

Antifreeze in the hot core of Orion - First detection of ethylene glycol in Orion-KL

Context. Ices are present in comets and in the mantles of interstellar grains. Their chemical composition has been indirectly derived by observing molecules released in the gas phase, when comets approach the sun and when ice mantles are sublimated or destroyed, e.g. in the hot cores present in high-mass, star-forming regions. Comparison of these chemical compositions sheds light...

Mastectomy rates remain high in Singapore and are not associated with poorer survival after adjusting for age

Recent reports have suggested that women undergoing mastectomy, instead of wide local excision (WLE) for Stage I and II breast cancers have poorer overall survival. This is particularly important in our setting where mastectomy rates are high. In this study, we evaluated the trends in mastectomy and WLE over a 10-year period at a single institute, identified factors more common...

Quantitative Mapping of Matrix Content and Distribution across the Ligament-to-Bone Insertion

The interface between bone and connective tissues such as the Anterior Cruciate Ligament (ACL) constitutes a complex transition traversing multiple tissue regions, including non-calcified and calcified fibrocartilage, which integrates and enables load transfer between otherwise structurally and functionally distinct tissue types. The objective of this study was to investigate...

Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells

Sustained activation of nuclear factor-κB (NF-κB) in cancer cells has been shown to promote inflammation, expansion of cancer stem cell (CSC) population, and tumor development. In contrast, recent studies reveal that CSCs exhibit increased inflammation due to constitutive NF-κB activation; however, the underlying molecular mechanism remains unclear. In the present study, the...

Ferroelectric tunnel junctions with graphene electrodes

, Lincoln, Nebraska 68588, USAE. Y. Tsymbal, A. Sinitskii & A. Gruverman AuthorsSearch for H. Lu in:Nature Research journals • PubMed • Google ScholarSearch for A. Lipatov in:Nature Research journals • PubMed ... Contributions A.G., A.S. and E.Y.T. conceived the idea, designed the experiment and wrote the paper. H. Lu and D.J.K. implemented experimental measurements. A.L. and A.S. performed fabrication and spectroscopic

Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers

Obesity, and in particular visceral obesity, has been associated with an increased risk of developing cancers as well as higher rates of mortality following diagnosis. The impact of obesity on adipose-derived stromal cells (ASC), which contribute to the formation of tumor stroma, is unknown. Here we hypothesized that visceral source and diet-induced obesity (DIO) changes the ASC...

Clinical Significance of CTNNB1 Mutation and Wnt Pathway Activation in Endometrioid Endometrial Carcinoma

Background Endometrioid endometrial carcinoma (EEC) is the most common form of endometrial carcinoma. The heterogeneous clinical course of EEC is an obstacle to individualized patient care.

Effects of Annealing Time on the Performance of OTFT on Glass with ZrO2 as Gate Dielectric

Copper phthalocyanine-based organic thin-film transistors (OTFTs) with zirconium oxide (ZrO2) as gate dielectric have been fabricated on glass substrates. The gate dielectric is annealed in N2 at different durations (5, 15, 40, and 60 min) to investigate the effects of annealing time on the electrical properties of the OTFTs. Experimental results show that the longer the...

Genomic variation in macrophage-cultured European porcine reproductive and respiratory syndrome virus Olot/91 revealed using ultra-deep next generation sequencing

Background Porcine Reproductive and Respiratory Syndrome (PRRS) is a disease of major economic impact worldwide. The etiologic agent of this disease is the PRRS virus (PRRSV). Increasing evidence suggest that microevolution within a coexisting quasispecies population can give rise to high sequence heterogeneity in PRRSV. Findings We developed a pipeline based on the ultra-deep...